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Nimesulide Dispersible Tablets

Function and Efficacy

This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is not yet fully understood, but it may be mainly related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes.

Ingredients

This product mainly contains nimesulide.

Name Description Content CAS NO. Manufacturer
NimesulideIngredients

This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is not yet fully understood, but it may be mainly related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes.

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51803-78-2 14

Appearance

This product is light yellow irregular tablets.

Indication

This product is a non-steroidal anti-inflammatory drug and is only used when at least one other non-steroidal anti-inflammatory drug has failed. It can be used for the pain of chronic arthritis (such as osteoarthritis), pain after surgery and acute trauma, and symptomatic treatment of primary dysmenorrhea.

Usage and Dosage

Oral administration: 0.05-0.1g at a time, twice a day, after meals. The maximum single dose should not exceed 100mg, and the course of treatment should not exceed 15 days. It is recommended to use the minimum effective dose and the shortest course of treatment to reduce the occurrence of adverse drug reactions.

Adverse Reactions

This product has fewer side effects. Common side effects are heartburn, stomach pain and gastrointestinal disorders, but the symptoms are mild and short-lived, and rarely require interruption of treatment. In rare cases, patients develop allergic rashes after taking it. Even if the above symptoms do not occur when using nimesulide, it should be noted that this product, like other non-steroidal anti-inflammatory drugs, may cause dizziness, drowsiness, gastric ulcers or gastrointestinal bleeding and Stevens-Johnson syndrome.

Precautions

1. Patients who are allergic to this product, acetylsalicylic acid or other non-steroidal drugs are contraindicated. 2. Patients with active gastrointestinal bleeding or active peptic ulcer are contraindicated. 3. Patients with severe liver dysfunction and severe renal dysfunction (creatinine clearance rate 30 ml/min) are contraindicated.

Special Population Medication

Precautions for children: Children under 12 years old are prohibited from using this medicine. Precautions for pregnancy and lactation: There are no tests to prove whether nimesulide is toxic to the fetus, so it is not recommended for pregnant women. It has not been confirmed whether nimesulide is excreted through breast milk, so it is not recommended for lactating women. Precautions for the elderly: Due to the decline in renal function in elderly patients, the dosage can be appropriately reduced according to the situation.

Drug Interactions

This product may cross-react with aspirin and other non-steroidal anti-inflammatory drugs. Therefore, it is contraindicated for patients who are allergic to these drugs. This product is a highly protein-bound drug, so it may displace other protein-bound drugs. If vision loss occurs after taking other non-steroidal anti-inflammatory drugs, treatment should be stopped and an ophthalmological examination should be performed.

Storage

Sealed and stored in a dry place.

Packaging Specification

0.1g

Validity Period

Tentatively two years.

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