Acemetacin extended-release capsules
Function and Efficacy
This product is a non-steroidal anti-inflammatory drug, which may produce anti-inflammatory, analgesic and antipyretic effects by inhibiting the synthesis of prostaglandins.
Ingredients
The main ingredient of this product is acemetacin.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| AcemetacinIngredients |
This product is a non-steroidal anti-inflammatory drug, which may produce anti-inflammatory, analgesic and antipyretic effects by inhibiting the synthesis of prostaglandins. More |
53164-05-9 | 4 |
Appearance
This product is a capsule, and the contents are light yellow powder.
Indication
1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis. 2. Periarthritis of shoulder, bursitis, tenosynovitis. 3. Low back pain, sprain, strain and other soft tissue injuries. 4. Acute gout. 5. Dysmenorrhea, toothache and postoperative pain.
Usage and Dosage
For adults, take orally with meals: 90 mg (1 tablet) once a day. If the condition is serious, the dosage can be increased to 180 mg (2 tablets) a day, or as directed by a doctor.
Adverse Reactions
1. The following side effects may occur occasionally: nausea, vomiting, abdominal pain, diarrhea, loss of appetite, occult blood in stool (may cause anemia in some cases), peptic ulcer (sometimes accompanied by bleeding and perforation), headache, dizziness, drowsiness/fatigue, tinnitus. Patients should consult a doctor immediately if they experience severe gastrointestinal disturbances, especially upper abdominal pain and black stools. 2. The following side effects rarely occur: anxiety, mental disorder, psychosis, hallucinations, depression, excitement, muscle weakness, peripheral neuropathy, kidney damage, edema, hypertension, hyperkalemia, highly allergic erythema, rash, mucosal rash, vascular (sperm) edema, hyperhidrosis, urticaria and itching, hair loss, allergic reactions, leukopenia, elevated liver enzymes, and elevated blood urea (nitrogen).
Precautions
It is contraindicated for patients with hematopoietic dysfunction and those who are allergic to acemetacin and indomethacin.
Special Population Medication
Precautions for children: Because there is no experience of using this product in children under 14 years old, it is not recommended. Precautions for pregnancy and lactation: Contraindicated.
Drug Interactions
The following interactions may occur when this product is taken with the following drugs: 1. Digoxin preparations - the concentration of digoxin in the blood may be increased when taken with digoxin preparations; 2. Lithium - patients receiving lithium treatment must monitor the clearance of lithium; 3. Anticoagulants - may increase the risk of bleeding (due to inhibition of thromboxane synthesis); 4. Adrenocorticoids or other non-steroidal anti-inflammatory drugs - increase the risk of gastrointestinal bleeding; 5. Acetylsalicylic acid - reduce the concentration of acemetacin in the blood; 6. Probenecid - can slow down the clearance of acemetacin; 7. Penicillin - this product can delay the clearance of penicillin; 8. Diuretics and antihypertensive drugs - this product can weaken their antihypertensive effects; 9. Furosemide - can
Storage
Store in a tightly closed, cool and dry place.
Packaging Specification
90 mg