Cetirizine Hydrochloride Tablets

[Pharmacology and Toxicology] This product is a selective histamine H1 receptor antagonist. Animal experiments show that this product has no obvious anticholinergic and anti-5-hydroxytryptamine effects, and is not easy to pass through the blood-cerebrospinal fluid barrier to act on the central H1 receptor. The central inhibitory effect is relatively mild in clinical use. [Pharmacology and Toxicology] According to data reports, it is absorbed by the gastrointestinal tract after oral administration. For healthy adults, taking 10 mg of cetirizine orally once, the peak time (tmax) of blood drug concentration is 30 to 60 minutes, and the peak blood drug concentration is 300ng/ml. Cetirizine has a high binding rate with plasma proteins. The plasma half-life is about 10 hours, and about 70% of the original drug is excreted in the urine, and a small amount is excreted in the feces.

The main ingredient of this product is cetirizine hydrochloride, and its chemical name is (±)-2-[2-[4-[(4-chlorophenyl)benzyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride.

This product is a film-coated tablet, which appears white or off-white after removing the film coating.

Used for seasonal or perennial allergic rhinitis, urticaria and skin itching caused by allergens.

Oral. Adults or children over 12 years old, 10 mg each time, once a day. Or follow the doctor's advice. If adverse reactions occur, it can be changed to 5 mg in the morning and evening. For children aged 6 to 11, the recommended starting dose is 5 mg or 10 mg once a day, depending on the severity of the symptoms. For children aged 2 to 5 years, the recommended starting dose is 2.5 mg once a day, and the maximum dose can be increased to 5 mg once a day, or 2.5 mg every 12 hours.

Adverse reactions are mild and transient, including drowsiness, sleepiness, headache, dizziness, agitation, dry mouth, and gastrointestinal discomfort. Occasionally, aspartate aminotransferase is slightly elevated.

It is contraindicated for those who are allergic to this product.

Precautions for children: Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly:

No interactions with other drugs have been reported, but caution should be exercised when taking sedatives at the same time.

Keep in a light-proof and airtight container.

10 mg

24 months

Qilu Pharmaceutical Co., Ltd.

• Founded in:

  1992-08-21

• Address:

  No. 317, Xinluo Street, High-tech Zone, Jinan City, Shandong Province

• Tax NO.:

  91370000614073351Q

• Registered Funds:

  600 million yuan

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