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Cefaclor Capsules

Function and Efficacy

Antibacterial drug. It is relatively stable against the β-lactamase produced by Staphylococcus aureus, so it has a strong antibacterial effect against Gram-positive bacteria; it is unstable against the β-lactamase produced by Gram-negative bacteria, so it has a weaker effect against Gram-negative bacteria, and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

Ingredients

The main ingredient of this product is cefaclor, and its chemical name is: (6R,7R)-7-[(R)-2-amino-2-phenylacetylamino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate

Name Description Content CAS NO. Manufacturer
CefaclorIngredients

Antibacterial drug. It is relatively stable against the β-lactamase produced by Staphylococcus aureus, so it has a strong antibacterial effect against Gram-positive bacteria; it is unstable against the β-lactamase produced by Gram-negative bacteria, so it has a weaker effect against Gram-negative bacteria, and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

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53994-73-3 29

Appearance

The content of this product is off-white to slightly yellow powder.

Indication

This product is mainly suitable for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.

Usage and Dosage

This product is suitable for oral administration on an empty stomach. The usual dosage for adults is 0.25g once, 3 times a day. In case of severe infection, the dosage can be doubled, but the total daily dosage should not exceed 4g, or follow the doctor's advice. Children are generally given 20mg/kg per day according to body weight, divided into 3 times. In severe infection, the dosage can be increased to 40mg/kg, but the total daily dosage should not exceed 1g.

Adverse Reactions

1. Gastrointestinal: diarrhea, stomach discomfort, nausea, vomiting, etc. 2. Allergic reaction: urticaria, rash, eosinophilia, vulvar pruritus. 3. Others: slight increase in aminotransferase, plasma urea nitrogen (BUN) and creatinine (Cr), proteinuria, casts, etc.

Precautions

Patients who are allergic to cefaclor and other cephalosporins are contraindicated.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other antineoplastic drugs and aminoglycoside antibiotics and other nephrotoxic drugs combined with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of β-lactamase. 3. Oral administration of probenecid can delay the excretion of this product.

Storage

Keep away from light, seal tightly, and store in a cool, dark, and dry place. Validity period: 24 months

Packaging Specification

0.25g

Validity Period

24 months

Manufacturer

Shanghai Huayuan Anhui Renji Pharmaceutical Co., Ltd.

  • Founded in:

    2000-03-17
  • Address:

    Area A, Taihe County Industrial Park, Anhui Province
  • Tax NO.:

    91341222152061697K
  • Registered Funds:

    38.105 million yuan
  • Website:

  • Email:

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