Pirenzepine Hydrochloride Tablets

This product is a selective anticholinergic drug, which has a high affinity for the muscarinic receptors of gastric parietal cells, but a low affinity for the muscarinic receptors of smooth muscle, myocardium and salivary glands, etc. Therefore, when used in general therapeutic doses, it can only inhibit gastric acid secretion, and rarely has side effects on pupils, gastrointestinal smooth muscle, heart, salivary glands and bladder muscles like other anticholinergic drugs. Increasing the dose can inhibit saliva secretion, and only large doses can inhibit gastrointestinal smooth muscle and cause tachycardia. This product cannot pass through the blood-brain barrier, so it does not affect the central nervous system. After oral, intramuscular or intravenous administration of this product, both the basal gastric acid secretion and the gastric acid secretion caused by exogenous pentagastrin and insulin are inhibited. This product has little effect on the pH of gastric juice, and mainly reduces the secretion of gastric juice (including pepsinogen and pepsin), thereby reducing the maximum gastric acid secretion and the highest acid secretion.

The main ingredients of this product are: Pirenzepine hydrochloride

This product is white or off-white tablet.

It is mainly used clinically for various acid-related diseases, such as duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, hyperacid gastritis, stress ulcer, acute gastric mucosal bleeding, gastrinoma, etc.

Oral administration: Adults, 25-50 mg at a time, twice a day, half an hour before breakfast and dinner.

It is related to the dose. Common adverse reactions include mild dry mouth, dry eyes and visual adjustment disorders, which disappear after stopping the drug. Occasionally, there are constipation, diarrhea, headache and mental confusion, which are generally mild and require discontinuation of the drug in 2%.

1. It is forbidden for those who are allergic to this product; 2. It is forbidden for pregnant women; 3. It is forbidden for those with glaucoma and prostate hypertrophy.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not for use by pregnant women. Precautions for the elderly: Not yet clear.

1. Ethanol and coffee can weaken the effect of this product; 2. H2 receptor antagonists can enhance the effect of this product.

Keep away from light and store in a sealed container.

25 mg

24 months

Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical General

• Founded in:

  1973-07-01

• Address:

  No. 88, Yunxiang Road, Tonghe Street, Baiyun District, Guangzhou

• Tax NO.:

  91440101714253245D

• Registered Funds:

  -

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