Gatifloxacin eye drops

Gatifloxacin is a DNA gyrase inhibitor and also a topoisomerase IV inhibitor. DNA gyrase (topoisomerase II) is a basic bacterial enzyme that maintains the helical structure of DNA and is essential in DNA replication, transcription, repair, recombination, and conversion and translocation. Therefore, Gatifloxacin is bactericidal.

The main ingredient of this product is gatifloxacin. Chemical name: 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid Molecular weight: C19H22FN3O4

This product is a yellowish green clear liquid.

The following infections caused by Staphylococcus, Streptococcus, Pneumococcus, Bacteria, Corynebacterium, Bacterium Burkholderia, Pseudomonas, Haemophilus influenzae, etc. that are sensitive to gatifloxacin: blepharitis, sty, dacryocystitis, conjunctivitis, tarsal gland inflammation, keratitis, corneal ulcer, etc.

Place 1 to 2 drops into the eyelids, 3 times a day, or as directed by your doctor.

Occasionally, there may be transient irritation symptoms

It is contraindicated for patients who are allergic to gatifloxacin or quinolones.

Precautions for children: The safety and effectiveness of this product for infants under 1 year old have not been established, so it should be used with caution in infants. Precautions for pregnancy and lactation: No teratogenic effects were found in rats and rabbits taking 50 mg/kg/day of gatifloxacin orally. However, oral administration of 150 mg/kg/day to rats can cause fetal skeletal/craniofacial malformations or delayed ossification, anterior chamber hypertrophy, and weight loss. Oral administration of 200 mg/kg/day during the perinatal period can cause miscarriage and increased perinatal mortality in fetal rats. Due to the lack of research data on the use of gatifloxacin by pregnant women, pregnant women should consult a doctor before using this product and only use it after weighing the pros and cons. Gatifloxacin can be secreted in the milk of rats, but it is not clear whether it is secreted in human milk. It should be used with caution in lactating women. Precautions for the elderly: There is no significant difference in the effectiveness and safety of gatifloxacin between elderly and young patients.

The interaction between gatifloxacin eye drops and other drugs is still unclear. However, systemic administration of quinolone antibiotics can increase the plasma concentration of theophylline, affect the metabolism of caffeine, enhance the efficacy of oral anticoagulants such as warfarin and its derivatives, and cause a transient increase in the plasma inosine level in patients taking cyclosporine. Please follow the doctor's advice when using the above drugs in combination.

Keep in dark, airtight, cool place

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24 months

Jiangsu Jibeier Pharmaceutical Co., Ltd.

• Founded in:

  2001-11-13

• Address:

  Zhenjiang High-tech Industrial Development Park

• Tax NO.:

  913211007317784571

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  199.430865 yuan

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