Sodium norcantharidate for injection
Function and Efficacy
In vitro tests of this product have a destructive or inhibitory effect on the morphology or proliferation of cell lines such as liver cancer, esophageal cancer, laryngeal cancer, lung cancer, and cervical cancer. In vivo tests have a certain inhibitory effect on mouse Ehrlich ascites carcinoma, sarcoma-180 and solid liver cancer. It can increase the respiratory control rate and lysosomal enzyme activity of mitochondria in H22 mouse ascites liver cancer cells, interfere with cancer cell division, block in the M phase, and affect its cycle speed. This product can destroy the skeleton of cancer cells (microfilaments, microtubules), affect the ultrastructure of cancer cells, and cause damage to mitochondria, microvilli and plasma membranes. It can inhibit DNA synthesis of cancer cells, but it does not inhibit normal bone marrow cells, and can increase white blood cells.
Ingredients
Main ingredients: The main active ingredient is sodium norcantharidin.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| SodiuM DeMethylcantharidateIngredients |
In vitro tests of this product have a destructive or inhibitory effect on the morphology or proliferation of cell lines such as liver cancer, esophageal cancer, laryngeal cancer, lung cancer, and cervical cancer. In vivo tests have a certain inhibitory effect on mouse Ehrlich ascites carcinoma, sarcoma-180 and solid liver cancer. It can increase the respiratory control rate and lysosomal enzyme activity of mitochondria in H22 mouse ascites liver cancer cells, interfere with cancer cell division, block in the M phase, and affect its cycle speed. This product can destroy the skeleton of cancer cells (microfilaments, microtubules), affect the ultrastructure of cancer cells, and cause damage to mitochondria, microvilli and plasma membranes. It can inhibit DNA synthesis of cancer cells, but it does not inhibit normal bone marrow cells, and can increase white blood cells. More |
13114-29-9 | 0 |
Indication
It has destructive and inhibitory effects on the morphology or proliferation of cell lines such as liver cancer, esophageal cancer, laryngeal cancer, lung cancer, and cervical cancer.
Usage and Dosage
1. Intravenous injection. Take this product, dissolve and dilute it with an appropriate amount of 5% glucose injection, and slowly push it intravenously. 10~30mg at a time or follow the doctor's advice. For intravenous drip, dissolve it with an appropriate amount of 5% glucose injection, add it to 250~500ml of 5% glucose injection and slowly drip it. 2. Hepatic artery catheterization. Take this product and dissolve it with an appropriate amount of sterile injection water for use. 10~30mg at a time, twice a day. One month is a course of treatment, and it usually lasts for 2~3 courses. 3. Intratumoral injection. Take this product and dissolve it with an appropriate amount of sterile injection water for use. 10~30mg at a time, once a week, 4 times as a course of treatment, and it can last for 4 courses.
Adverse Reactions
If the single injection volume exceeds 30 mg, some patients may experience gastrointestinal symptoms such as nausea and vomiting. The dose can be reduced or symptomatic treatment can be given.
Precautions
It is contraindicated for those who are allergic to this product.
Drug Interactions
Not yet clear.
Storage
Keep tightly closed.
Packaging Specification
10mg (as norcantharidin)
Manufacturer
Shaanxi Bosen Biological Pharmaceutical Group Co., Ltd.
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Founded in:
2002-12-12 -
Address:
No. 7, Chuangxin Road, New Industrial Park, High-tech Zone, Xi'an, Shaanxi Province -
Tax NO.:
91610000745007979F -
Registered Funds:
171 million yuan -
Website:
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Email: