Levothyroxine Sodium Tablets

Pharmacological action: The synthetic levothyroxine contained in this product is identical to the thyroxine naturally secreted by the thyroid gland. Like endogenous hormones, it is converted to T3 in peripheral organs and then exerts its specific effects by binding to T3 receptors. The human body cannot distinguish between endogenous and exogenous levothyroxine. ?Toxicological action: Chronic toxicity studies in animals of different species (rats, dogs) have found that when rats are given high doses of levothyroxine sodium, signs of liver disease, an increased incidence of spontaneous nephropathy, and changes in organ weights occur. Only a very small amount of ineffective thyroid hormone crosses the placenta. Sufficient human test data have shown that the use of levothyroxine at different stages of pregnancy has no toxic effects on the fetus and does not cause malformations. There are no reports that this product will impair male or female fertility, nor is there any indication that fertility impairment is related to this product. There is no information on the mutagenicity of this product. So far, there is no indication that thyroid hormones can cause genomic changes that harm offspring. No long-term animal tests have been conducted on the carcinogenicity of levothyroxine.

The main ingredient of this product is levothyroxine sodium. Molecular weight: C15H10I4NNaO4·XH2O

This product is white or off-white round tablets.

1. Treatment of non-toxic goiter (normal thyroid function); 2. Prevention of goiter recurrence after thyroidectomy; 3. Replacement therapy for hypothyroidism; 4. Adjuvant therapy for hyperthyroidism with antithyroid drugs; 5. Suppressive therapy after thyroid cancer surgery; 6. Thyroid suppression test.

See instructions for details.

If the individual tolerance dose is exceeded or the drug is overdosed, especially due to a rapid increase in the dose at the beginning of treatment, the following clinical symptoms of hyperthyroidism may occur, including: tachycardia, palpitations, arrhythmia, angina, headache, muscle weakness and cramps, flushing, fever, vomiting, menstrual disorders, pseudotumor cerebri, tremor, restlessness, insomnia, sweating, weight loss and diarrhea. In the above cases, the patient's daily dose should be reduced or the drug should be stopped for a few days. Once the above symptoms disappear, the patient should restart the drug treatment with caution. Patients who are allergic to the ingredients in this product may experience allergic reactions, especially skin and respiratory allergic reactions. Cases of angioedema have been reported.

Those who are highly sensitive to this product and its excipients. Untreated adrenal insufficiency, pituitary insufficiency and thyrotoxicosis. Acute myocardial infarction, acute myocarditis and acute pancarditis. During pregnancy, this product should not be used in combination with antithyroid drugs to treat hyperthyroidism.

Precautions for children: Please refer to "Dosage and Administration". Precautions for pregnancy and lactation: Special attention should be paid to continued use of thyroid hormone treatment during pregnancy and lactation. The dose of this product may be increased during pregnancy. There are no reports that this product causes teratogenicity and/or fetal toxicity at the recommended therapeutic dose in humans. Excessive use of high doses of levothyroxine by pregnant women may have adverse reactions to the fetus or postnatal development of the fetus. At the recommended therapeutic dose, the amount of thyroid hormone exuded into breast milk during breastfeeding is not enough to cause hyperthyroidism or suppression of TSH secretion in the infant. Levothyroxine should not be used in combination with antithyroid drugs to treat hyperthyroidism during pregnancy because the addition of levothyroxine increases the dose of antithyroid drugs. Radioactive substances are contraindicated in pregnant women, so thyroid suppression diagnostic tests should be avoided during pregnancy. Pregnant women should note: Please refer to "Dosage and Administration".

See instructions for details.

Light-proof and airtight.

50μg*100s (Euthyrox)

24 months