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Cetirizine Sustained-Release Tablets

Function and Efficacy

This product is a compound preparation composed of cetirizine hydrochloride and pseudoephedrine hydrochloride. Cetirizine is a selective histamine H1 receptor antagonist. It has no obvious anticholinergic and anti-5-hydroxytryptamine effects, and has a small central inhibitory effect; pseudoephedrine hydrochloride is an adrenergic drug that can constrict nasal mucosal blood vessels and relieve symptoms of nasal congestion and runny nose.

Ingredients

This product is a compound preparation, its components are: cetirizine hydrochloride, pseudoephedrine hydrochloride. Each tablet contains 5mg of cetirizine hydrochloride and 120mg of pseudoephedrine hydrochloride.

Name Description Content CAS NO. Manufacturer
Cetirizine dihydrochlorideIngredients

Selective histamine H1 receptor antagonist. No obvious anticholinergic and anti-5-hydroxytryptamine effects, and less central nervous system inhibitory effect

More
83881-52-1 58

Appearance

This product is a film-coated tablet, which appears white or off-white after removing the film coating.

Indication

This product is suitable for the treatment of year-round and seasonal allergic rhinitis and the treatment of allergic rhinitis with nasal congestion symptoms.

Usage and Dosage

Oral administration: Adults and children over 12 years old, 1 tablet at a time, 2 times a day.

Adverse Reactions

Adverse reactions of cetirizine hydrochloride include drowsiness, fatigue, dry mouth, pharyngitis, dizziness, etc.; pseudoephedrine hydrochloride may cause nervousness, dizziness, restlessness, insomnia, and mild central nervous system excitation in allergic people.

Precautions

This product is contraindicated in patients who have allergic or idiosyncratic reactions to the ingredients contained in this product, hydroxyzine, adrenergic drugs, or other drugs with similar chemical structures. This product is contraindicated in patients who are currently receiving monoamine oxidase inhibitors or have received such treatment within 14 days or have just stopped such treatment. This product is also contraindicated in patients with narrow-angle glaucoma, urinary retention, severe hypertension or severe coronary artery disease.

Drug Interactions

In the study of interactions in adults, no drug interactions were found when cetirizine was used in combination with pseudoephedrine, antipyrine, ketoconazole, erythromycin and azithromycin. When cetirizine (20 mg, once a day for three consecutive days) was used in combination with theophylline (400 mg, once a day for three consecutive days), it was found that the clearance of cetirizine decreased by 16%. Therefore, cetirizine and theophylline should not be used together.

Storage

Keep away from light and sealed. Validity period: 24 months

Packaging Specification

Each tablet contains 5 mg of cetirizine hydrochloride and 120 mg of pseudoephedrine hydrochloride

Manufacturer

Jinling Pharmaceutical Co., Ltd. Nanjing Jinling Pharmaceutical Factory

  • Founded in:

    1996-09-16
  • Address:

    No. 58, Xingang Avenue, Nanjing Economic and Technological Development Zone
  • Tax NO.:

    9132019270413930XB
  • Registered Funds:

    -
  • Email:

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