Aripiprazole tablets

Aripiprazole has a high affinity for dopamine D2, D3, 5-HT1A and 5-HT2A receptors, and a moderate affinity for D4, 5-HT2c, 5-HT7, a1, H1 receptors and 5-HT reabsorption sites. Aripiprazole produces its anti-schizophrenia effect through partial agonism of D2 and 5-HT1A receptors and antagonism of 5-HT2A receptors.

Aripiprazole. 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydroquinolinone

This product is white tablets.

1. For the treatment of schizophrenia. 2. The efficacy of aripiprazole in the treatment of schizophrenia has been established in short-term (4-week and 6-week) controlled trials in patients with schizophrenia. Physicians who choose aripiprazole for long-term treatment should regularly re-evaluate the long-term efficacy of the drug for individual patients.

Take orally once a day, with an initial dose of 5 mg/day in the first week and an increase to 10 mg/day in the second week. After 2 weeks of medication, the dose can be increased to 15 mg/day based on individual efficacy and tolerance. The maximum daily dose should not exceed 30 mg.

Body: Common - influenza syndrome, peripheral edema, chest pain, neck pain, stiff neck; Uncommon - pelvic pain, suicidal tendencies, facial edema, malaise, photosensitivity, arm stiffness, jaw pain, chills, bloating, tight jaw, enlarged abdomen, chest tightness; Rare - sore throat, tight back, heavy head, candidiasis, tight throat, stiff legs, tight neck, Meniere's syndrome, heat stroke. Cardiovascular System: Common - hypertension, tachycardia, hypotension, bradycardia; Uncommon - palpitations, hemorrhage, myocardial infarction, QT interval prolongation, cardiac arrest, atrial fibrillation, heart failure, AV block, myocardial ischemia, phlebitis, deep vein thrombosis, angina, extrasystoles; Rare - vasovagal reaction, cardiomegaly, atrial flutter, thrombophlebitis. Digestive System:

Patients with known hypersensitivity to this product are contraindicated.

Precautions for children: There is currently a lack of sufficient clinical experience in children. Precautions for pregnancy and lactation: It is not clear whether this product is safe for pregnant women to take. For pregnant women, the pros and cons should be weighed to decide whether to take this product. It can only be used when the potential benefits outweigh the risks, otherwise it should not be taken during pregnancy and lactation. Precautions for the elderly: Aripiprazole is well tolerated by the elderly at the recommended dose and no dose adjustment is required.

1. Use with caution when combined with other drugs that act on the central nervous system and alcohol. 2. Aripiprazole may enhance the effects of certain antihypertensive drugs. 3. CYP3A4 inducers (such as carbamazepine) will increase the clearance rate of aripiprazole and reduce its blood concentration. CYP3A4 inhibitors (such as ketoconazole) or CYP2D inhibitors (such as quinidine, fluoxetine, paroxetine) can inhibit the elimination of aripiprazole and increase its blood concentration.

Keep sealed.

5mg

24 months