Metronidazole lotion

Metronidazole has a strong antibacterial effect on most anaerobic bacteria, but has no effect on aerobic bacteria and facultative anaerobes. The antibacterial spectrum includes Bacteroides fragilis and other Bacteroides, Fusobacterium, Clostridium perfringens, Eubacterium, Veillonella, Peptococcus and Peptostreptococcus. Its bactericidal concentration is slightly higher than the inhibitory concentration. The bactericidal mechanism of metronidazole has not been fully elucidated. The nitroreductase of anaerobic bacteria plays an important role in the energy metabolism of sensitive strains. The nitro group of this product is reduced to a cytotoxin, thereby acting on the DNA metabolism process of bacteria and promoting cell death.

The main ingredient of this product is metronidazole.

This product is a colorless or slightly yellow clear liquid.

This product is a preventive medicine that can prevent anaerobic infection. It is used in the following situations: 1. Postoperative intracavitary and incision flushing. 2. Local medication for various wound infections such as the bile duct, pelvic cavity, abdominal cavity, and chest cavity. 3. For deep tissue abscesses, use this product to flush the abscess cavity after puncture and drainage.

This product can be used directly to flush wounds or abscesses, or made into gauze or gauze strips for wet compresses. It can also be used for continuous irrigation of deep abscesses, and the dosage depends on the wound and infection conditions.

Local adverse reactions are rare. Because this product can be absorbed from the wound, large-scale use can produce the same adverse reactions as systemic medication: 1. It can cause epileptic seizures and peripheral neuropathy, the latter of which is mainly manifested as numbness and paresthesia of the extremities. In some cases, long-term use of the drug may cause persistent peripheral neuropathy. 2. Other common adverse reactions include: (1) Gastrointestinal reactions, such as nausea, loss of appetite, vomiting, diarrhea, abdominal discomfort, taste changes, dry mouth, metallic taste in the mouth, etc. (2) Reversible neutropenia. (3) Allergic reactions, rash, urticaria, itching, etc. (4) Central nervous system symptoms, such as headache, dizziness, syncope, paresthesia, limb numbness, ataxia and mental confusion. (5) Others include fever, vaginal candidiasis, cystitis,

It is contraindicated for patients who are allergic to this product or azole drugs and those with active central nervous system diseases and blood diseases.

When used in large quantities, this product may be absorbed through wounds and may produce drug interactions similar to those of systemic medications, such as inhibiting the metabolism of warfarin and other oral anticoagulants, interfering with disulfiram metabolism and serum aminotransferase and lactate dehydrogenase assay results, and combining it with liver microsomal enzyme inducers or inhibitors may speed up or slow down the metabolism of this product in the liver.

Keep away from light and store in a sealed container.

500ml: Metronidazole 1g and sodium chloride 4.5g

Sichuan Kelun Pharmaceutical Co., Ltd.

• Founded in:

  2002-05-29

• Address:

  South 2nd Road, Xindu Satellite City Industrial Development Zone, Chengdu

• Tax NO.:

  9151010020260067X4

• Registered Funds:

  1,601,497,373 yuan

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