Betamethasone Tablets

Glucocorticoid drugs. They have multiple pharmacological effects such as anti-inflammatory, anti-allergic and immunosuppressive, and are widely used in clinical practice. 1 Anti-inflammatory effect: Glucocorticoids reduce and prevent tissue responses to inflammation, thereby reducing the manifestations of inflammation. 2 Immunosuppressive effect: Prevent or inhibit cell-mediated immune responses, delayed allergic reactions, reduce the number of T lymphocytes, monocytes and eosinophils, reduce the ability of immunoglobulins to bind to cell surface receptors, and inhibit the synthesis and release of interleukins, thereby reducing the transformation of T cells into lymphoblasts and reducing the expansion of primary immune responses. 3 Anti-toxic and anti-shock effects: Glucocorticoids can counteract the stimulating response of bacterial endotoxins to the body, reduce

16β-methyl-11β,17α,21-trihydroxy-9α-pregna-1,4-diene-3,20-dione

This product is white tablets.

It is mainly used for allergic and autoimmune inflammatory diseases. It is now used for active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukemia, etc. It is also used for the comprehensive treatment of certain infections.

The initial oral dose is 1-4 mg per day, given in divided doses. The maintenance dose is 0.5-1 mg per day.

There are no obvious adverse reactions when glucocorticoids are used in physiological dose replacement therapy. Adverse reactions mostly occur when pharmacological doses are used, and are closely related to the course of treatment, dosage, type of medication, usage and route of administration. Common adverse reactions are as follows: 1. Long-term use may cause the following side effects: iatrogenic Cushing's syndrome facial and body shape, weight gain, lower limb edema, purple lines, easy bleeding tendency, poor wound healing, acne, menstrual disorders, avascular necrosis of the humeral or femoral head, osteoporosis and fractures (including vertebral compression fractures, pathological fractures of long bones), muscle weakness, muscular atrophy, hypokalemia syndrome, gastrointestinal irritation (nausea, vomiting), pancreatitis, peptic ulcer or perforation, growth inhibition in children, glaucoma, cataracts, benign intracranial pressure

Patients who are allergic to this product and other steroid hormones are prohibited from using it. Patients with the following diseases should not use it in general. In special cases, the pros and cons should be weighed, but attention should be paid to the possibility of worsening of the condition: severe mental illness (past or present) and epilepsy, active peptic ulcer disease, recent gastrointestinal anastomosis, fractures, trauma repair period, corneal ulcer, hyperadrenocortical syndrome, hypertension, diabetes, pregnant women, infections that cannot be controlled by antibacterial drugs such as chickenpox, measles, fungal infections, severe osteoporosis, etc.

Precautions for children: Children should be very cautious when using adrenocortical hormones for a long time. Precautions for pregnancy and lactation: Generally not suitable for use. Precautions for the elderly: Elderly patients are prone to hypertension and diabetes when using glucocorticoids. Elderly patients, especially postmenopausal women, are prone to aggravating osteoporosis when using glucocorticoids.

1. Nonsteroidal anti-inflammatory analgesics can enhance its ulcerogenic effect. 2. It can enhance the hepatotoxicity of acetaminophen. 3. When used in combination with amphotericin B or carbonic anhydrase inhibitors, it can aggravate hypokalemia. Long-term use with carbonic anhydrase inhibitors can easily lead to hypocalcemia and osteoporosis. 4. When used in combination with protein anabolic hormones, it can increase the incidence of edema and aggravate acne. 5. Long-term use with anticholinergics (such as atropine) can cause increased intraocular pressure. 6. Tricyclic antidepressants can aggravate the mental symptoms caused by them. 7. When used in combination with hypoglycemic drugs such as insulin, it can increase blood sugar in diabetic patients.

Keep away from light and store in sealed container.

0.5mg

24 months