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Acyclovir Tablets

Function and Efficacy

The antiviral drug has an inhibitory effect on herpes simplex virus, varicella zoster virus, cytomegalovirus, etc. in vitro. This product has a special affinity for viruses, but has low toxicity to mammalian host cells.

Ingredients

Its chemical structure: Molecular formula: C8H11N5O3 Molecular weight: 225.21.

Appearance

This product is white tablets.

Indication

1. Herpes simplex virus infection: used for initial and recurrent cases of genital herpes virus infection. For recurrent cases, this product can be taken orally for prevention. 2. Herpes zoster: used for the treatment of herpes zoster in patients with normal immune function and mild cases in immunocompromised patients. 3. Treatment of varicella in immunocompromised patients.

Usage and Dosage

1 Genital herpes for the first time and immunocompromised patients with simple herpes simplex on the skin and mucous membranes: 0.4g once, 3 times a day, for 5 days. 2 Herpes zoster: The usual dose for adults is 0.8g once, 5 times a day, for 7-10 days. 3 Varicella: Children over 2 years old should take 20mg/kg of body weight once, 4 times a day, for 5 days. Start treatment immediately when symptoms appear. The usual dose for children over 40kg and adults is 0.8g once, 4 times a day, for 5 days.

Adverse Reactions

Occasionally, there may be dizziness, headache, joint pain, nausea and vomiting.

Precautions

Those who are allergic to this product are prohibited from using it.

Special Population Medication

Precautions for children: The dosage for children under 2 years old has not been determined. Precautions for pregnancy and lactation: The drug can pass through the placenta. Although animal experiments have confirmed that it has no effect on the embryo, pregnant women still need to weigh the pros and cons of using the drug. The concentration of the drug in breast milk is 0.6 to 4.1 times the blood concentration. Although no abnormalities have been found in infants, breastfeeding women should use it with caution. Precautions for the elderly: Due to the decline of physiological renal function, the dosage and medication interval of this product need to be adjusted.

Drug Interactions

1. Combination with zidovudine can cause nephrotoxicity, manifested as deep lethargy and fatigue. 2. Competitive inhibition of organic acid secretion with probenecid. Combination with probenecid can slow down the excretion of this product, prolong the half-life, and accumulate the drug in the body.

Storage

Keep tightly closed in a cool, dry place.

Packaging Specification

0.1 g

Validity Period

36 months

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