Etoposide Soft Capsules
Function and Efficacy
This product is a cell cycle-specific anti-tumor drug that acts on DNA topoisomerase II to form a stable reversible complex of drug-enzyme-DNA, which hinders DNA repair. Experiments have found that this complex can be reversed with the elimination of the drug, allowing the damaged DNA to be repaired and reducing cytotoxicity. Therefore, extending the drug administration time may improve the anti-tumor activity.
Ingredients
The main ingredient of this product is etoposide.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| EtoposideIngredients |
Cell cycle-specific anti-tumor drugs act on DNA topoisomerase II to form a stable reversible drug-enzyme-DNA complex that hinders DNA repair. Experiments have found that this complex can be reversed as the drug is removed, allowing damaged DNA to be repaired and reducing cytotoxic effects. Therefore, extending the drug administration time may increase anti-tumor activity. More |
33419-42-0 | 20 |
Appearance
This product is a soft capsule, the contents of which are colorless or light yellow clear viscous liquid.
Indication
It is mainly used to treat small cell lung cancer, malignant lymphoma, malignant germ cell tumor, leukemia, and has certain therapeutic effects on neuroblastoma, rhabdomyosarcoma, ovarian cancer, non-small cell lung cancer, gastric cancer and esophageal cancer.
Usage and Dosage
Single use: 60-100 mg/m2 per day for 10 consecutive days, repeated every 3-4 weeks. Combined chemotherapy: 50 mg/m2/day for 3 or 5 consecutive days.
Adverse Reactions
The main toxicity is hematological and gastrointestinal toxicity. Compared with intravenous preparations, the incidence of vomiting is lower. Severe allergic reactions may occur in rare cases and should be taken seriously.
Precautions
People who are allergic to this product, pregnant women and breastfeeding women are forbidden to use it.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not allowed. Precautions for the elderly: Not yet clear.
Drug Interactions
Not yet clear.
Storage
Keep away from light, tightly closed, in a cool place.
Packaging Specification
50mg
Validity Period
24 months