Chlorethoxyquinoxaline Dropping Pills

Chlorethoxyquin is a non-steroidal estrogen drug with weaker activity than diethylstilbestrol. It can regulate the release of gonadotropin from the anterior pituitary gland, and by reducing the release of luteinizing hormone-releasing factor from the hypothalamus, it leads to lower release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. Because its effect on causing hyperfunction of the anterior pituitary gland and adrenal cortex is weaker than that of estrogen, long-term use will not cause pituitary enlargement and adrenal hyperplasia. It has a relatively mild effect and is well tolerated by the human body.

The main ingredient of this product is niclosamide. Its chemical name is 4-nitro-2,5-dichlorosalicylic anilide. Molecular formula: C23H21ClO3 Molecular weight: 380.87

It is a white or off-white crystalline powder, odorless. It is easily soluble in chloroform, benzene or acetone, soluble in ether, slightly soluble in methanol or ethanol, and almost insoluble in water. This medicine is a white or milky white pill.

Used to treat women's menopausal syndrome and symptoms caused by estrogen deficiency after surgery; dysfunctional uterine bleeding in adolescence; estrogen replacement therapy for women with hypogonadism; and prostate hyperplasia in men.

Oral administration. 1. Symptoms caused by menopausal syndrome and postoperative estrogen deficiency in women: daily dose 4-12 mg, 20-22 days as a course of treatment, 7 days after stopping the drug, start another course of treatment, after the symptoms improve, the dose can be gradually reduced. 2. Dysfunctional uterine bleeding in adolescence: daily dose 20-80 mg, taken in 2-3 times, reduce as appropriate after bleeding stops, daily maintenance dose 8 mg. 3. Female hypogonadism: daily dose 8-12 mg, take for 21 consecutive days, stop the drug for 7 days and take again. It can be increased or decreased according to personal conditions. 4. Prostatic hyperplasia: daily dose 12-24 mg, 4-8 weeks as a course of treatment, if necessary, it can be extended or follow the doctor's advice.

Occasionally, mild stomach discomfort, nausea, vomiting, dizziness, breast tenderness, vaginal bleeding, drowsiness, frequent urination, painful urination, headache, abdominal pain, chest pain, rash, etc. may occur.

It is contraindicated in patients with undiagnosed gynecological bleeding, a history of cholestatic jaundice, a history of thrombosis, breast cancer, and suspected estrogen-related tumors.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: This product has teratogenic effects on the fetus and can be secreted in breast milk, so it is not suitable for pregnant and lactating women. Precautions for the elderly: Not yet clear.

1. When used in combination with anticoagulants, the anticoagulant effect is weakened. 2. When used in combination with phenobarbital, phenytoin sodium, and primidone, the effect of this product may be reduced. 3. When used in combination with tricyclic antidepressants, the latter's adverse reactions increase and the effect is weakened.

Store in a dark, airtight, cool place.

4 mg

24 months

Suzhou First Pharmacertical Co., Ltd.

• Founded in:

  2005-12-23

• Address:

  No. 1 Hualing Street, Suzhou Industrial Park

• Tax NO.:

  91320594783360722P

• Registered Funds:

  181.625 million yuan

• Email:

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