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Piperazine ferulate tablets

Function and Efficacy

1. Pharmacology: This product has the effects of anticoagulation, antiplatelet aggregation, dilation of microvessels, increase of coronary flow, and relief of vascular spasm. 2. Toxicology: The results of acute toxicity experiments show that the oral LD50 of the first-class Kunming mice is: 3580.1 plus mn; 251.7 mg/kg, with a confidence limit of 95%. The results of long-term toxicity studies show that the long-term toxicity experiment results of intravenous injection of 300 mg of piperazine ferulate (30 times in a row) every other day on healthy adult male dogs prove that piperazine ferulate has low toxicity and can be used clinically. Reproductive toxicity studies show that no obvious embryotoxicity and teratogenicity were observed in Wistar rats by intraperitoneal injection and oral gavage, indicating that the drug is basically safe and reliable in terms of teratogenicity. The results of carcinogenicity studies show that the mutagenic effect of piperazine ferulate on Salmonella typhimurium TA98 and TA100, the test of piperazine ferulate bone marrow micronucleus and the test of the effect of piperazine ferulate on chromosome aberration of mouse bone marrow cells show that this product has no carcinogenicity.

Ingredients

The active ingredient of this product is piperazine ferulate.

Name Description Content CAS NO. Manufacturer
Piperazine FerulateIngredients

Anticoagulation, antiplatelet aggregation, dilation of microvessels, increase of coronary flow, relief of vascular spasm

More
171876-65-6 5

Indication

This product is suitable for the auxiliary treatment of various glomerular diseases accompanied by microscopic hematuria and hypercoagulable state, such as nephritis, chronic nephritis, nephrotic syndrome, early uremia, as well as coronary heart disease, cerebral infarction, vasculitis, etc.

Usage and Dosage

Oral administration: 100-200 mg (2-4 tablets) at a time, 3 times a day.

Adverse Reactions

No relevant reports found

Precautions

It is contraindicated for patients who are allergic to piperazine ferulate drugs.

Drug Interactions

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

Storage

Keep away from light and store in sealed container.

Packaging Specification

100mg

Validity Period

24 months.

Manufacturer

Chengdu Hengda Pharmaceutical Co., Ltd.

  • Founded in:

    2007-03-13
  • Address:

    No. 598, Section 3, East Third Ring Road, Pengzhou City, Sichuan Province
  • Tax NO.:

    91510182202545973X
  • Registered Funds:

    31.25 million yuan
  • Website:

  • Email:

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