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o-Iodine [131I] Sodium Hippurate Injection

Function and Efficacy

After intravenous injection, this product immediately enters the kidney with the blood flow and is quickly cleared by the kidney. 80% of it is secreted by the renal tubules without reabsorption, and 20% is filtered by the glomerulus. The o-iodine hippurate sodium that passes through the nephron is flushed to the renal calyx and renal pelvis through the collecting duct and discharged into the bladder through the ureter. 30 minutes after intravenous injection, the amount of o-iodine hippurate sodium in the urine can reach 70% of the injected amount.

Ingredients

The main component and chemical name of this product are: hippuric acid labeled with iodine [131I]. Its structural formula is: Molecular formula: C9H7131INNaO3

Indication

Tests of kidney and urinary system function.

Usage and Dosage

Renal function test: intravenous injection of 185~370kBq (5~10Ci), nephrography for 15~20 minutes, no preparation is required for the patient. Dynamic renal imaging: intravenous injection of 11.1~18.5MBq (0.3~0.5mCi), under normal circumstances, initially showing renal parenchyma, then the peripheral images gradually fade, and the radioactivity is concentrated in the renal pelvis. After about 15 minutes, the renal pelvis shadow also becomes significantly lighter, and the radioactivity is concentrated in the bladder.

Adverse Reactions

This product occasionally causes adverse reactions. The subjects may experience cold sweats, back pain, and in severe cases, collapse. In case of adverse reactions, the injection should be stopped and symptomatic treatment should be given.

Precautions

It is contraindicated for those who are allergic to this product.

Drug Interactions

Not yet clear.

Storage

Place in a lead container and keep it airtight. The radiation level on the surface of the lead container should meet the requirements.

Packaging Specification

37MBq

Manufacturer

Chengdu Gaotong Isotope Co., Ltd.

  • Founded in:

    2002-06-11
  • Address:

    Floor 28, Unit 1, Building 1, No. 166, Mingdu Road, Chengdu Hi-Tech Zone
  • Tax NO.:

    91510100737746894Y
  • Registered Funds:

    70,583,407 yuan
  • Website:

  • Email:

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