Netilmicin Sulfate and Glucose Injection

This product is a semi-synthetic aminoglycoside antibiotic with strong antibacterial activity and a broad antibacterial spectrum. It has high antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Klebsiella, Enterobacter, Serratia, Citrobacter, Proteus (indole-positive and indole-negative), Salmonella, Shigella, Haemophilus influenzae, etc.; it is also highly sensitive to certain species such as Pseudomonas aeruginosa, Mycobacterium tuberculosis, Providencia and Acinetobacter; it has antibacterial activity against most Staphylococci, including methicillin-sensitive strains. Aminoglycoside antibiotics are one of the commonly used drugs in clinical practice in China. This drug is mainly used for infections caused by sensitive Gram-negative bacteria, with an efficacy of about 80%. As a routine drug for preventing infection in surgical operations, it can significantly reduce the incidence of infection in oropharyngeal, hand and chest operations, and the incidence of drug resistance in abdominal operations. Compared with cephalosporin antibiotics, the incidence of bacterial resistance to netilmicin is much lower. The third generation of cephalosporin 19% and netilmicin 1% are highly safe for the ears and kidneys. Netilmicin sulfate for injection also has the post-aminoglycoside antibiotic effect, that is, after the bacteria are exposed to antibiotics, although the antibiotics are no longer present, there is still a certain inhibitory effect, and it takes a certain amount of time for the bacteria to resume normal growth. Therefore, once-a-day administration can achieve the effect of treating the disease. Kanglixing is effective in treating infectious diseases in various clinical departments, respiratory system 98%, digestive system 100%, urinary system 98%, surgical infection 97.8%, gynecological infection 86%, pediatric pneumonia 99%, burn infection 83%, skin infection 91%, gonorrhea 100%, bacillary dysentery 100%, clinical efficacy evaluation: domestic data, foreign data, mechanism of action: This product is an aminoglycoside antibiotic, which mainly acts on the ribosomes in bacteria and inhibits the synthesis of bacterial proteins. Aminoglycoside antibiotics have a strong bactericidal effect.

Netilmicin Sulfate

This product is a colorless or almost colorless clear liquid.

It is suitable for the short-term treatment of serious or life-threatening bacterial infections caused by sensitive bacteria {Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter, Proteus mirabilis, Proteus (indole-positive), Serratia and Citrobacter, and Staphylococcus aureus}, including infants, children and other patients of all ages. These infectious diseases include: 1. Complicated urinary tract infection; 2. Sepsis; 3. Skin tissue infection; 4. Intra-abdominal infection, including peritonitis and intra-abdominal abscess; 5. Lower respiratory tract infection.

This product is slowly dripped intravenously. For complicated urinary tract infection in adults, 3-4 mg/kg per day, divided into 2 times; for severe systemic infection: 4-6.5 mg/kg per day, divided into 2-3 times. For newborns: the total daily dosage is 4-6 mg/kg per day, divided into 2 times; for children aged 6-12 years, the total daily dosage is 5.5-8.0 mg/kg, divided into 2-3 times. The course of treatment for this product varies depending on the type of disease and condition, and is generally 7-14 days.

This product has mild adverse reactions: (1) Nephrotoxicity, which is mild and rare. Nephrotoxicity often occurs in patients with pre-existing renal impairment or those who use doses exceeding the usual dose; (2) Rare nervous system toxicity; (3) Others: Occasionally, headache, general discomfort, visual impairment, palpitations, rash, fever, vomiting and diarrhea may occur, and blood sugar, blood alkaline phosphatase, serum transaminase, etc. may increase, white blood cell and platelet count may decrease, and eosinophils may increase.

Patients who are allergic to this product or any aminoglycoside antibiotics or have severe toxic reactions are contraindicated.

1 Avoid using this product in combination with other nephrotoxic and neurotoxic drugs such as aminoglycoside antibiotics, vancomycin, polymyxin, strong diuretics and neuromuscular blocking drugs. 2 Mixing this product with β-lactams (cephalosporins or penicillins) may lead to mutual inactivation. When combined use is required, it must be dripped in separate bottles; this product should not be dripped in the same bottle with other drugs.

Keep away from light and store in a sealed container.

100ml: Netilmicin sulfate 100,000 units and glucose 5.0g

Cisen Pharmaceutical Co., Ltd.

• Founded in:

  1998-11-06

• Address:

  Tongji Science and Technology Industrial Park, Jining High-tech Zone

• Tax NO.:

  91370800706117999P

• Registered Funds:

  452,754,129 yuan

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