Compound mebendazole cream
Function and Efficacy
1. Tobacillus thuringiensis is a derivative of benzimidazole. This type of drug has a strong affinity for the beta-tubulin of the insect body and can bind to it at very low concentrations, thereby inhibiting the polymerization of microtubules, causing the disappearance of the epidermis or intestinal cells of the insect body, reducing digestion and reducing the absorption of nutrients such as glucose, leading to the death of the insect body. 2. This drug can also inhibit fumarate reductase in mitochondria, reduce glucose transport, and uncouple oxidative phosphorylation, thereby affecting the production of ATP. 3. This drug has an effect on both adults and eggs. Animal experiments have shown that it can be absorbed through the skin, and the concentration of the drug in the intestinal cavity is higher than that in plasma, showing a good anthelmintic effect.
Ingredients
Main ingredients and chemical names: mebendazole and levamisole hydrochloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| MebendazoleIngredients |
Mebendazole is a derivative of benzimidazole. This type of drug has a strong affinity for the beta-tubulin of the insect body and can bind to it at very low concentrations, thereby inhibiting the polymerization of microtubules, causing the disappearance of the epidermis or intestinal cells of the insect body, reducing digestion and reducing the absorption of nutrients such as glucose, leading to the death of the insect body. This drug can also inhibit fumarate reductase in mitochondria, reduce glucose transport, and uncouple oxidative phosphorylation, thereby affecting the production of ATP. This drug has an effect on both adults and eggs. Animal experiments have shown that it can be absorbed through the skin, and the concentration of the drug in the intestinal cavity is higher than that in plasma, showing a good anthelmintic effect. More |
31431-39-7 | 8 | |
| Levamisole hydrochlorideIngredients |
1. Tobacillus thuringiensis is a derivative of benzimidazole. This type of drug has a strong affinity for the beta-tubulin of the insect body and can bind to it at very low concentrations, thereby inhibiting the polymerization of microtubules, causing the disappearance of the epidermis or intestinal cells of the insect body, reducing digestion and reducing the absorption of nutrients such as glucose, leading to the death of the insect body. 2. This drug can also inhibit fumarate reductase in mitochondria, reduce glucose transport, and uncouple oxidative phosphorylation, thereby affecting the production of ATP. 3. This drug has an effect on both adults and eggs. Animal experiments have shown that it can be absorbed through the skin, and the concentration of the drug in the intestinal cavity is higher than that in plasma, showing a good anthelmintic effect. More |
16595-80-5 | 7 |
Appearance
This product is a light pink cream with an emulsion base.
Indication
Used to expel roundworms and pinworms.
Usage and Dosage
Children over 6 years old and adults use 1 tube at a time, children between 2 and 6 years old use half a tube. Apply to the skin once, around the navel of the abdomen or the skin on the inner thigh, with an area of about 20×20cm2.
Adverse Reactions
1. Very few patients may have gastrointestinal irritation symptoms such as nausea, abdominal discomfort, loss of appetite, etc. 2. Levamisole hydrochloride can cause nausea, vomiting, dizziness, abdominal discomfort, loss of appetite, etc. Mebendazole can cause nausea, headache, dizziness, fatigue, insomnia, etc.
Precautions
1. Those who are allergic to imidazole drugs. 2. Those with active hepatitis.
Special Population Medication
Precautions for children: Not for use in children under 2 years old. Precautions for pregnancy and lactation: Not for use in pregnant and lactating women. Precautions for the elderly: No such experiment has been conducted and there is no reliable reference literature.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
1g: Contains 0.1g of levamisole hydrochloride and 0.15g of mebendazole
Validity Period
24 months