Acetylspiramycin Capsules
Ingredients
This product is a mixture of four main components: monoacetylspiramycin II, monoacetylspiramycin III, diacetylspiramycin II and diacetylspiramycin III.
Appearance
This product is in the form of capsules.
Usage and Dosage
Adult dose: 0.2-0.3g once, 4 times a day, double the dosage for the first dose. Pediatric dose: 20-30mg/kg per day, divided into 4 doses.
Adverse Reactions
Patients tolerated the drug well. Adverse reactions mainly included gastrointestinal reactions such as abdominal pain, nausea, and vomiting, which often occurred when taking large doses. Most of them were mild and disappeared on their own after stopping the drug. Allergic reactions were rare, mainly drug eruptions. No liver or kidney damage or abnormal blood or urine routine tests were found.
Precautions
Patients who are allergic to this product, erythromycin, or other macrolides are contraindicated.
Special Population Medication
Precautions for children: The efficacy and safety of pediatric patients under 6 months old have not been determined. Precautions for pregnancy and lactation: This product can penetrate the placenta, so the use of it in pregnant women needs to be determined after fully weighing the pros and cons. There is no data showing whether acetylspiramycin is excreted through breast milk, but since many macrolide drugs can be excreted through breast milk, lactating women should use this product with caution. If it must be used, breastfeeding should be suspended. Precautions for the elderly: Elderly patients with normal liver and kidney function do not need to reduce the dosage.
Drug Interactions
1. This product does not affect the metabolism of aminophylline and other drugs in the body. 2. In patients receiving ergot derivatives, ergot poisoning has occurred when certain macrolides are used at the same time. There are currently no reports of ergot and acetylspiramycin interacting, but this possibility still exists in theory. Therefore, acetylspiramycin and ergot should not be taken at the same time.
Storage
Seal tightly and store in a dry and cool place.
Packaging Specification
0.2g*24s
Validity Period
36 months