Prulifloxacin Tablets
Function and Efficacy
This product has a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria, and especially exhibits strong antibacterial activity against Gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacter. Compared with norfloxacin, ofloxacin, levofloxacin, ciprofloxacin, tosufloxacin, fleroxacin, sparfloxacin, etc., the in vitro test shows that the antibacterial activity of this product is equal to or exceeds that of norfloxacin, ofloxacin, levofloxacin, ciprofloxacin, tosufloxacin, fleroxacin, sparfloxacin, etc. In particular, the antibacterial activity against intestinal flora with MIC90 (μg/ml) of Escherichia coli (0.1), Citrobacter bisporus (0.1), Enterobacter aerogenes (0.2), Proteus mirabilis (≤0.05), Proteus vulgaris (≤0.05), and Proteus morganii (0.39) is the strongest. The MIC90 against Pseudomonas aeruginosa is 0.39μg/ml, which far exceeds the antibacterial activity of the above-mentioned other floxacins.
Ingredients
Prulifloxacin. Chemical name: (±)-6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-1-piperazinyl]-4-oxo-4-hydrogen-[1,3]thiazine[3,2-α]quinoline-3-carboxylic acid Molecular weight: C21H20FN3O6S
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| PrulifloxacinIngredients |
It has a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria, and is particularly effective against Gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacter. In vitro tests show that its antibacterial activity is as good as or better than that of norfloxacin, ofloxacin, levofloxacin, ciprofloxacin, tosufloxacin, fleroxacin, sparfloxacin, etc., and is particularly effective against intestinal flora with MIC90 (μg/ml) of Escherichia coli (0.1), Citrobacter bisporus (0.1), Enterobacter aerogenes (0.2), Proteus mirabilis (≤0.05), Proteus vulgaris (≤0.05), and Proteus morganii (0.39). The MIC90 against Pseudomonas aeruginosa is 0.39μg/ml, far exceeding the antibacterial activity of the above-mentioned other floxacins. More |
123447-62-1 | 14 |
Appearance
This product is light yellow tablet.
Indication
No data yet
Usage and Dosage
Adults: 0.2-0.3 g bid, the dose can be adjusted appropriately according to symptoms.
Adverse Reactions
Gastrointestinal reactions, increased AST (GOT) and ALT (GPT). Allergic reactions. Rare Achilles tendinitis, tendon rupture and other tendon disorders, rhabdomyolysis, hypoglycemia, abnormal blood count, liver/renal dysfunction, arrhythmia, QT interval prolongation, severe colitis, spasm, mental confusion, depression and other mental symptoms.
Precautions
1. Patients with severe renal impairment [Because the high blood concentration continues, the dosage should be reduced or the interval between doses should be limited] 2. Patients with convulsive diseases such as epilepsy or who have had such diseases
Special Population Medication
Precautions for children: Do not use this product because its safety has not been established for low-birth-weight infants, newborns, nursing infants, infants and children. Precautions for pregnancy and lactation: The safety of this product for pregnant and lactating women has not been established. Lactating women should stop breastfeeding when taking this product. Precautions for the elderly: The half-life of this product is prolonged after the elderly take it.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
Light-proof and sealed.
Packaging Specification
132mg (equivalent to 100mg of prulifloxacin active ingredient)
Validity Period
24 months
Manufacturer
Hainan Hailing Chemipharma Corporation Ltd.
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Founded in:
2004-04-01 -
Address:
No. 281 Nanhai Avenue, Haikou City -
Tax NO.:
91460000760353116G -
Registered Funds:
116.669422 million yuan -
Website:
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Email: