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Aspirin tablets

Function and Efficacy

This product belongs to non-steroidal anti-inflammatory drugs. 1 Analgesic effect: It is mainly through inhibiting the synthesis of prostaglandins and other substances that can make pain sensitive to mechanical or chemical stimulation (such as bradykinin, histamine), and it belongs to peripheral analgesics. However, the possibility of central analgesia (possibly acting on the hypothalamus) cannot be ruled out; 2 Anti-inflammatory effect: The exact mechanism is still unclear. It may be due to the fact that this product acts on inflamed tissues and inhibits the synthesis of prostaglandins or other substances that can cause inflammatory reactions (such as histamine) to play an anti-inflammatory role. Inhibition of the release of lysosomal enzymes and leukocyte chemotaxis may also be related to it; 3 Antipyretic effect: It may act on the hypothalamic temperature regulation center to cause peripheral vasodilation, increased skin blood flow, sweating, and increased heat dissipation to play an antipyretic role. This central effect may be related to the inhibition of prostaglandin synthesis in the hypothalamus; 4 Anti-rheumatic effect: The anti-rheumatic mechanism of this product, in addition to antipyretic and analgesic effects, mainly lies in anti-inflammatory effect: 5 Inhibitory effect on platelet aggregation: It works by inhibiting platelet cyclooxygenase and reducing the production of prostaglandins.

Ingredients

Its chemical name is: 2-(acetoxy)benzoic acid. Structural formula: Molecular formula: C9H8O4 Molecular weight: 180.16

Indication

1. Used for fever, headache, neuralgia, muscle pain, rheumatic fever, acute rheumatic arthritis and rheumatoid arthritis, etc. It is the first choice for rheumatic fever, rheumatic arthritis and rheumatoid arthritis, and can quickly relieve the symptoms of acute rheumatic arthritis. It can be used in combination with corticosteroids for patients with acute rheumatic fever accompanied by myocarditis. 2. Used for gout. 3. Prevent myocardial infarction, arterial thrombosis, atherosclerosis, etc. 4. Used to treat biliary ascariasis (effectiveness over 90%). 5. Powder for external use, can treat tinea pedis.

Usage and Dosage

1 Antipyretic and analgesic: 0.3-0.6g orally each time, 3 times a day, or when needed; 2 Anti-rheumatic: 0.5-1g each time, 3-5 times a day. It is advisable to chew it orally, and it can be used together with calcium carbonate or aluminum hydroxide or Wei Shuping to reduce gastric irritation. One course of treatment is about 3 months. Children take 0.1g per kilogram of body weight per day, divided into 3 times, and take half the dose in the first 3 days to reduce reactions; 3 Prevention of myocardial infarction, arterial thrombosis, and atherosclerosis, once a day, 0.3g each time; prevention of transient cerebral ischemia, 0.65g each time, twice a day; 4 Treatment of biliary ascariasis: 1g each time, 2-3 times a day, for 2-3 consecutive days. Stop the drug when the paroxysmal colic stops for 24 hours, and then perform routine deworming; 5 Treatment of diarrhea caused by X-ray irradiation or radiotherapy: take 0.6-0.9g each time, 4 times a day.

Adverse Reactions

This product is a compound tablet mainly composed of aspirin and phenacetin. The more common adverse reactions of aspirin include gastrointestinal reactions such as nausea, vomiting, upper abdominal discomfort or pain, which usually disappear after stopping the drug; gastrointestinal bleeding or ulcers may occur when used for a long time or in large quantities; reversible symptoms may occur after taking a certain course of treatment.

Precautions

It is contraindicated for patients who are allergic to aspirin or other nonsteroidal anti-inflammatory drugs and caffeine, hemophilia, active peptic ulcer and other gastrointestinal bleeding. It is contraindicated for infants under 3 months old.

Drug Interactions

1. It should not be used together with similar preparations containing this product and other antipyretic analgesics; 2. This product should not be used together with anticoagulants (such as dicoumarol, heparin) and thrombolytics (streptokinase); 3. Antacids such as sodium bicarbonate can increase the excretion of this product in the urine and reduce the blood concentration, so they should not be used together; 4. This product can increase gastrointestinal adverse reactions when used together with glucocorticoids (such as dexamethasone); 5. This product can enhance the effects of oral hypoglycemic drugs and methotrexate, so they should not be used together; 6. If you are taking other medicines, please consult a physician or pharmacist before taking this product.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

0.3g

Manufacturer

Yunnan Mingjing Pharmaceutical Co., Ltd.

  • Founded in:

    2004-02-12
  • Address:

    No. 1 Tuanjie Huacaochang Road, Xishan District, Kunming City, Yunnan Province
  • Tax NO.:

    9153000075718143X2
  • Registered Funds:

    20 million yuan
  • Website:

  • Email:

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