Nefopam Hydrochloride Injection

This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. The chemical structure belongs to cyclized o-methylbenzylamine. Therefore, it does not have the characteristics of non-steroidal anti-inflammatory drugs, nor is it an opioid receptor agonist. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no inhibitory effect on the circulatory system. There is no tolerance and dependence. Acute toxicity LD50 (mg/kg): mice, oral 66.6; intraperitoneal 28.7; intravenous 21.9. Rats, oral 178; intramuscular injection 56.9.

Nefopam Hydrochloride

This product is a colorless clear liquid.

It is used for postoperative analgesia, cancer pain, acute traumatic pain. It is also used for visceral smooth muscle colic such as acute gastritis, biliary ascariasis, ureteral stones, etc. It is also used as an auxiliary drug for local anesthesia, acupuncture anesthesia, etc.

Intramuscular or intravenous injection: 20 mg at a time, or every 3 to 4 hours if necessary.

When the effects occur, there are often drowsiness, nausea, sweating, dizziness, headache, etc. But it usually does not last long. Occasionally, dry mouth, dizziness, and rash are seen.

It is contraindicated in patients with severe cardiovascular disease, myocardial infarction or convulsions.

Precautions for children: There is still a lack of data on the efficacy and safety of this product for children. Precautions for pregnancy and lactation: The effect on pregnant women is not yet clear. Since the concentration of the drug in breast milk is equivalent to that in plasma, lactating women should follow the doctor's advice when using it. Precautions for the elderly: There is still a lack of data on the efficacy and safety of this product for elderly patients.

1. This product should not be used in combination with anticonvulsants. 2. This product should not be used in combination with monoamine oxidase inhibitors. 3. When this product is used in combination with codeine, pentazocine, and dextropropoxyphene, the adverse reactions and addiction of the latter are enhanced.

Keep away from light and store in a sealed container.

1ml:20mg

24 months

Shanghai Modern Hasen (Shangqiu) Pharmaceutical Co., Ltd.

• Founded in:

  1999-11-12

• Address:

  No. 166, North side of Xinxing Road, west side of Zhenxing Road, Liangyuan District, Shangqiu City

• Tax NO.:

  91411400716735619N

• Registered Funds:

  83.29 million yuan

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