Potassium Magnesium Aspartate for Injection

Potassium magnesium aspartate is a mixture of potassium aspartate and magnesium salt, and is an electroporation supplement. Magnesium and magnesium are important cations in cells, and play an important role in a variety of enzyme reactions and muscle contraction processes. The ratio of extracellular potassium ions, calcium ions, sodium ions, and magnesium ions affects myocardial contractility. Aspartate is the precursor of oxaloacetate in the body and plays an important role in the tricarboxylic acid cycle. At the same time, aspartate also participates in the ornithine cycle, promoting the metabolism of ammonia and carbon dioxide, generating urea, and reducing the content of ammonia and carbon dioxide in the blood. Aspartate has a strong affinity with cells and can be used as a carrier for potassium and magnesium ions to enter cells, allowing potassium ions to return to cells, promoting cell depolarization and cell metabolism, and maintaining their normal functions. Magnesium ions are indispensable substances for the production of glycogen and high-energy phosphates, and can enhance the therapeutic effect of potassium aspartate. No obvious toxicity or side effects were observed at the commonly used clinical doses. The LO50 of intravenous injection in mice is greater than 700 mg/kg.

This product is a compound preparation, each bottle contains 1.7g of L-aspartic acid, 0.228g of potassium and 0.084g of magnesium

This product is white freeze-dried powder or lump.

Electrolyte supplement. It can be used for adjuvant treatment of hypokalemia, arrhythmias (mainly ventricular arrhythmias) caused by digitalis poisoning, and sequelae of myocarditis, congestive heart failure, and myocardial infarction.

Intravenous drip, 1-3 bottles per day, diluted in 250-500ml of 0.9% sodium chloride or 5%-10% glucose solution and slowly drip intravenously or as directed by a doctor.

Too fast an infusion may cause hyperkalemia and hypermagnesemia, as well as nausea, vomiting, facial flushing, chest tightness, decreased blood pressure, and occasional vascular irritation pain. Large doses may cause diarrhea.

Hyperkalemia, acute and chronic renal failure, Addison's disease, III0 atrioventricular block, cardiogenic shock (blood pressure below 90 mmHg).

Precautions for children: There is no reliable data to show that this product has any toxic effects on children. Precautions for pregnancy and lactation: It is not clear yet, it is recommended to use this product with caution. Precautions for the elderly: The kidney clearance capacity of the elderly is reduced, so it should be used with caution.

Hyperkalemia may occur when this product is used in combination with potassium-sparing diuretics and/or angiotensin-converting enzyme inhibitors (ACEIs).

Keep tightly closed.

2.0g (Potassium aspartate 1.0g and Magnesium aspartate 1.0g)

24 months

Shanxi PUDE Pharmaceutical Co., Ltd.

• Founded in:

  1995-09-13

• Address:

  The First Pharmaceutical Park, Datong Economic and Technological Development Zone, Shanxi Province

• Tax NO.:

  91140200602167297K

• Registered Funds:

  138.8 million yuan

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