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Pamidronate Disodium for Injection

Function and Efficacy

This product is a bisphosphonate drug. In vitro and animal tests have shown that it can strongly inhibit the dissolution of hydroxyapatite and the activity of osteoclasts, and has a very significant inhibitory effect on bone absorption. It has an analgesic effect on pain caused by osteolytic bone metastasis of cancer, and can also be used to treat hypercalcemia caused by cancer.

Ingredients

The chemical name is: 3-amino-1-hydroxypropylidene-1,1-diphosphonic acid disodium pentahydrate.

Indication

Hypercalcemia complicated by malignancy and bone pain caused by osteolytic cancer metastasis.

Usage and Dosage

Treatment of bone metastasis pain: dilute in 0.9% saline or 5% glucose solution without calcium ions before use. Slow intravenous drip for more than 4 hours, the concentration should not exceed 15mg/125ml, and the drip rate should not be greater than 15-30mg/2 hours. 30-60mg per dose. Treatment of hypercalcemia: medication should be used strictly according to blood calcium concentration and under the guidance of a doctor.

Adverse Reactions

A small number of patients may experience mild nausea, chest pain, chest tightness, dizziness, fatigue, and slight changes in liver and kidney function, and occasionally fever.

Precautions

Patients with a history of allergy to this product and bisphosphonates are contraindicated.

Drug Interactions

Not yet clear.

Storage

Keep away from light, tightly closed, in a cool place.

Packaging Specification

15mg

Manufacturer

Shanxi PUDE Pharmaceutical Co., Ltd.

  • Founded in:

    1995-09-13
  • Address:

    The First Pharmaceutical Park, Datong Economic and Technological Development Zone, Shanxi Province
  • Tax NO.:

    91140200602167297K
  • Registered Funds:

    138.8 million yuan
  • Website:

  • Email:

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