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Gliclazide Tablets

Function and Efficacy

This product is a second-generation sulfonylurea hypoglycemic drug with a strong effect. Its mechanism is to selectively act on pancreatic β cells, promote insulin secretion, and increase the level of glucose after eating glucose, so that the production and output of glycogen are inhibited. Animal experiments and clinical use have shown that this product can reduce platelet aggregation and adhesion, and help prevent and treat diabetic microangiopathy.

Ingredients

The main ingredient is: Gliclazide. Its chemical name is: 1-(3-azabicyclo[3.3.0]octyl)-3-p-toluenesulfonylurea.

Name Description Content CAS NO. Manufacturer
GliclazideIngredients

The second generation of sulfonylurea hypoglycemic drugs has a strong effect, selectively acting on pancreatic β cells, promoting insulin secretion, and improving the response after eating glucose; inhibiting the production and output of glycogen. Animal experiments and clinical use have proven that it can reduce platelet aggregation and adhesion, and help prevent and treat diabetic microangiopathy.

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Appearance

This product is white tablets.

Usage and Dosage

It should be taken under the guidance of a physician, with an initial oral dose of 40-80 mg, 1-2 times a day, and then adjusted to 80-240 mg a day, divided into 2-3 doses, based on blood and urine sugar levels. After blood and urine sugar levels are controlled, the daily maintenance dose can be changed. Elderly patients should reduce the dose as appropriate.

Adverse Reactions

Occasionally, there may be mild nausea, vomiting, upper abdominal pain, constipation, diarrhea, erythema, urticaria, thrombocytopenia, granulocytopenia, anemia, etc. Most of them disappear after stopping the drug.

Precautions

1. Patients with impaired liver and kidney function are contraindicated. 2. Patients allergic to sulfonylureas are contraindicated.

Special Population Medication

Precautions for children: Not clear yet. Precautions for pregnancy and lactation: Animal experiments and clinical observations have shown that sulfonylurea hypoglycemic drugs can cause teratogenesis and are excreted through breast milk, so pregnant women and nursing mothers should not use them. Precautions for the elderly: The dosage should be appropriately reduced.

Drug Interactions

When used in combination with non-steroidal anti-inflammatory drugs (especially salicylates), sulfonamide antibiotics, coumarin anticoagulants, monoamine oxidase inhibitors, beta-receptor blockers, benzodiazepines, tetracycline, chloramphenicol, dicyclohexine, clofibrate, ethanol and other drugs, the dosage should be reduced to avoid hypoglycemia.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

80mg

Validity Period

24 months

Manufacturer

Harbin Pharmaceutical Group Co., Ltd. GENERAL Pharm. FACTORY

  • Founded in:

    1994-05-19
  • Address:

    No. 388, Hahei Highway, Hulan District (production base No. 109, Xuefu Road, Nangang District, No. 1, Junmin Street, Xiangfang District)
  • Tax NO.:

    912301008280277137
  • Registered Funds:

    -
  • Website:

  • Email:

Other Drugs of Harbin Pharmaceutical Group Co., Ltd. GENERAL Pharm. FACTORY

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