Amoxicillin Capsules

Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.

The main ingredients of this product are: Amoxicillin

This product is in the form of capsules.

1. Otitis media, sinusitis, pharyngitis, tonsillitis and other upper respiratory tract infections caused by hemolytic streptococci, pneumococcus, staphylococcus or Haemophilus influenzae. 2. Urogenital tract infections caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3. Skin and soft tissue infections caused by hemolytic streptococci, staphylococcus or Escherichia coli. 4. Acute bronchitis, pneumonia and other lower respiratory tract infections caused by hemolytic streptococci, pneumococcus, staphylococcus or Haemophilus influenzae. 5. Acute simple gonorrhea. 6. This product can also be used to treat typhoid fever, typhoid carriers and leptospirosis; amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate gastric and duodenal Helicobacter pylori and reduce the recurrence rate of peptic ulcers.

1. Adults: 0.5g at a time, once every 6 to 8 hours, and the daily dose shall not exceed 4g; 2. The daily dose for children is 20 to 40mg/Kg based on body weight, once every 8 hours; the daily dose for infants under 3 months old is 30mg/Kg based on body weight, once every 12 hours; 3. The dosage needs to be adjusted for patients with severe renal impairment, among which patients with endogenous creatinine clearance of 10 to 30ml/min should take 0.25 to 0.5g every 12 hours; patients with endogenous creatinine clearance of less than 10ml/min should take 0.25 to 0.5g every 24 hours.

1. Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis; 2. Allergic reactions such as rash, drug fever and asthma; 3. Anemia, thrombocytopenia, eosinophilia, etc.; 4. Serum aminotransferase may be slightly increased; 5. Superinfection caused by Candida or resistant bacteria; 6. Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior.

It is contraindicated in patients with penicillin allergy or penicillin skin test positive.

Precautions for children: 1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but their clinical significance is unclear. Precautions for pregnancy and lactation: Animal reproduction studies have shown that amoxicillin at 10 times the human dose did not damage the fertility and fetus of rats and mice. However, there is still a lack of sufficient controlled studies in humans. Given that animal reproduction studies cannot fully predict human reactions, pregnant women should only use this product when it is really necessary. Since a small amount of amoxicillin can be secreted in breast milk, it may cause allergies in infants after being taken by nursing mothers. Precautions for the elderly: It is not yet clear.

1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but their clinical significance is unclear.

Keep in a sealed container

Calculated as C16H19N3O5S 0.25 g

36 months