4-(4-bromophenyl)-5-methyl-2-(1,4,5,7-tetramethylpyrrolo[3,4-d]pyridazin-6-yl)-1,3-thiazole

4-chloro-2-(6-naphthalen-1-yl-4-phenylpyridin-2-yl)phenol

4-methyl-3-(6-methyl-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)benzenesulfonamide

4-(3-chlorophenyl)-5-(4-ethylpiperazin-1-yl)-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4-[4-(4-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-9-methyl-5H-pyrimido[5,4-b]indole

4-[5-[(Z)-[2-(4-methylphenyl)imino-4-oxo-3-(2-phenylethyl)-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoic acid

4-[3-(azepan-1-ylsulfonyl)phenyl]-3-(2-methoxyethyl)-N-phenyl-1,3-thiazol-2-imine

4-(3,4-dimethoxyphenyl)-13-propyl-10-thia-3,5,6,8,13-pentazatetracyclo[7.7.0.02,6.011,16]hexadeca-1(9),2,4,7,11(16)-pentaene

4-[4-(3-chlorophenyl)piperazin-1-yl]-8-ethoxy-5H-pyrimido[5,4-b]indole

4-(4-methoxyphenyl)-11-methyl-5-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4-[3-(azepan-1-ylsulfonyl)phenyl]-2-phenyl-1,3-thiazole

4-(3,4-dimethylphenyl)-5-hydroxy-7,8-dimethylbenzo[g][1,3]benzoxathiol-2-one

4-chloro-2-[4-(4-fluorophenyl)-6-phenylpyridin-2-yl]phenol

4-tert-butyl-N-[5-cyano-7-(3-methoxypropyl)-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaen-6-ylidene]benzamide

4-amino-N-[(4-methoxyphenyl)methyl]-3-methyl-2-sulfanylidene-1,3-thiazole-5-carboxamide

4-(3-chlorophenyl)-5-[2-(dimethylamino)ethylamino]-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4-(4-benzylpiperidin-1-yl)-8-methoxy-5-methylpyrimido[5,4-b]indole

4-(4-bromophenyl)-10-phenyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene

4-(3-chlorophenyl)-5-[4-(2-hydroxyethyl)piperazin-1-yl]-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4-(2-benzylsulfanylspiro[6H-benzo[h]quinazoline-5,1'-cyclopentane]-4-yl)morpholine

4-[(2,4-dichlorophenyl)methylsulfanyl]-2-methyl-[1]benzofuro[3,2-d]pyrimidine

4-(2,4-dimethoxyphenyl)-10-(3-methylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene

4-[10-(3,4-dimethylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl]phenol

4-(4-benzylpiperazin-1-yl)-9-methyl-5H-pyrimido[5,4-b]indole

4-tert-butyl-N-[5-cyano-7-(3-ethoxypropyl)-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaen-6-ylidene]benzamide

4,10-bis(3,4-dichlorophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene

4-(3-chlorophenyl)-11-methyl-5-morpholin-4-yl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4,4-dimethyl-15-methylsulfanyl-8-propan-2-yl-N-(pyridin-2-ylmethyl)-5-oxa-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1(10),2(7),8,12(17),13,15-hexaen-13-amine

4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-6,8-dimethylchromen-2-one

4-(2,3-dimethylphenyl)-6,17-dioxa-4-azatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraen-16-one

4-[4-(2,5-dimethylphenyl)piperazin-1-yl]-8-fluoro-5H-pyrimido[5,4-b]indole

4-methyl-3-thiophen-2-yl-5-[[3-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole

4-[[2-[(4-prop-2-enyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]benzamide

4-[(2-chlorophenyl)methylsulfanyl]-2-ethyl-[1]benzofuro[3,2-d]pyrimidine

4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-5,7-dimethylchromen-2-one

4-[10-(3-chlorophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl]phenol

4-[10-(3-chloro-4-methylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl]benzene-1,3-diol

4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-2-phenyl-[1]benzofuro[3,2-d]pyrimidine

4-(4-methoxyphenyl)-N,N-diphenylpiperazine-1-carboxamide

4-[4-[(2,4-dichlorophenyl)methyl]piperazin-1-yl]-2-phenyl-[1]benzofuro[3,2-d]pyrimidine

4-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]pyridine

4-[(5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid

4-methoxy-N-(7-methyl-1-propylpyrazolo[3,4-b]quinolin-3-yl)benzamide

4-chloro-N-[1-(2-methylpropyl)pyrazolo[3,4-b]quinolin-3-yl]benzamide

4-(5-bromo-3-methyl-1-benzofuran-2-yl)-6-methylchromen-2-one

4-[3-(azepan-1-ylsulfonyl)phenyl]-3-(3-methoxypropyl)-N-phenyl-1,3-thiazol-2-imine

4,4-dimethyl-15-methylsulfanyl-N-(3-morpholin-4-ylpropyl)-8-propan-2-yl-5-oxa-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1(10),2(7),8,12(17),13,15-hexaen-13-amine

4-chloro-N-[(2-oxo-1H-quinolin-4-yl)methyl]-N-propylbenzamide

4-(3-chlorophenyl)-11-methyl-5-(3-morpholin-4-ylpropylamino)-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4-[(5-naphthalen-1-yl-1,3,4-oxadiazol-2-yl)sulfanyl]but-2-ynyl 4-fluorobenzoate

4-[4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl]-5-thiophen-2-ylthieno[2,3-d]pyrimidine

4-chloro-N-[[2-methoxy-5-(3-methyl-4-oxophthalazin-1-yl)phenyl]methyl]benzamide

4-(4-cyclohexylpiperazin-1-yl)-7-methoxy-5H-pyrimido[5,4-b]indole

4-(3,5-dimethylphenoxy)-2-(4-propan-2-yloxyphenyl)quinazoline

4-[2,5-dimethyl-3-[(Z)-(3-methyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]pyrrol-1-yl]benzenesulfonamide

4-[[2-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]benzamide

4-[10-(3-chloro-4-methylphenyl)-3,4,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-5-yl]phenol

4-O-ethyl 2-O-prop-2-enyl 5-[[(Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-2-cyanoethenyl]amino]-3-methylthiophene-2,4-dicarboxylate

4-(3-chlorophenyl)-5-(2-hydroxyethylamino)-11-methyl-8-thia-4,6,11-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one

4-(4-benzylpiperazin-1-yl)-9-methoxy-5H-pyrimido[5,4-b]indole

4-[(5-naphthalen-1-yl-1,3,4-oxadiazol-2-yl)sulfanyl]but-2-ynyl 4-methoxybenzoate

4-(2-oxochromen-3-yl)-N-[2-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]benzamide

4-(2,4-dichlorophenyl)-10-(4-methylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene

4-[4-(2-benzhydryloxyethyl)piperazin-1-yl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine

4-hydroxy-3-phenyl-5-[[5-[[3-(trifluoromethyl)phenyl]methyl]-1,3-thiazol-2-yl]iminomethyl]-1,3-thiazole-2-thione

4-[(4-methoxyphenyl)methyl]-6,17-dioxa-4-azatetracyclo[8.7.0.02,7.011,15]heptadeca-1(10),2(7),8,11(15)-tetraen-16-one