Oleanicacid Pharma Grade

1. Reduce liver damage: oleanolic acid as the pentacyclic triterpene compound, acute or chronic liver injury of rats caused by carbon tetrachloride has obvious protective effect. After treatment, swelling of mitochondria and the expansion of rough endoplasmic reticulum restoration. Still can make acute and chronic liver injury of ballooning degeneration, necrosis of liver cells and inflammatory reaction significantly reduce. Accumulation of triglycerides in the liver decreased, glycogen content increased.

2. Reduce the serum Alt activity: oleanolic acid on acute and chronic hepatitis and liver cirrhosis animals have significantly reduced enzyme action.

3. Reduce the r - serum globulin, and related to the histological observation of liver inflammation ease is consistent.

4. Promote the regeneration of the hepatocytes: oleanolic acid can induce the number of nuclear division phase residual liver of rats obviously increased, renewable degrees higher than the control group, tip can promote cell regeneration.

5. Lower levels of cirrhosis rats homogenate cool glycine: due to significantly lower level of brain homogenate and cool glycine, inhibits generate pseudo neurotransmitters, therefore, is beneficial to the prevention and therapy of hepatic encephalopathy.

6. Inhibiting liver fiber hyperplasia: oleanolic acid treatment of liver fibrosis in rats, hepatic fiber hyperplasia serious and significantly reduce, reduce liver collagen content, prompt has the effect of prevention and treatment of liver cirrhosis.

7. Oleanolic acid in mice mononuclear phagocyte system, macrophage phagocytosis and experimental arthritis has obvious inhibitory effect, but to the opposite sex have an impact on the humoral immune function and the antigen cells. Enhance immunity and inhibit the growth of S180 tumor strains.

8. On chromosome damage has a protective effect of experimental atherosclerosis has prevention effect, still can correct the protein metabolism disorder.