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Trifluoroacetic acid

11 Inquiries

Unit Price: Get Latest Price
CAS No.:

76-05-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Any China Port

Packaging:

1kg/as customer's requirment

Price valid (until):

2020-07-02

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

API,Intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  



      Specification  


    Melting point -15 °C
    Boiling point 72.4 °C(lit.)
    density 1.535 g/mL at 25 °C(lit.)
    vapor density 3.9 (vs air)
    vapor pressure 97.5 mm Hg ( 20 °C)
    refractive index n20/D 1.3(lit.)
    Fp None
    storage temp. 2-8°C
    solubility Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4
    form Liquid
    pka-0.3(at 25℃)
    color Colorless
    Specific Gravity1.480
    OdorSharp, pungent odor
    PH1 (10g/l, H2O)
    PH Range1
    Water Solubility miscible
    λmaxλ: 260 nm Amax: 0.9
    λ: 270 nm Amax: 0.10
    λ: 280 nm Amax: 0.05
    λ: 290 nm Amax: 0.04
    λ: 300 nm Amax: 0.03
    λ: 320 nm Amax: 0.025
    Sensitive Hygroscopic
    Merck 14,9681
    BRN 742035
    Stability:Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases.
    InChIKeyDTQVDTLACAAQTR-UHFFFAOYSA-N
    CAS DataBase Reference76-05-1(CAS DataBase Reference)
    NIST Chemistry ReferenceAcetic acid, trifluoro-(76-05-1)
    EPA Substance Registry SystemAcetic acid, 2,2,2-trifluoro- (76-05-1)

    Basic Info
    Product Name:

    Trifluoroacetic acid

    Other Name:

    RARECHEM AL BO 0421;PERFLUOROACETIC ACID;TRIFLUOROACETIC ACID;TRIFLUOROACETLC ACID;IPC-PFFA-2;trifluoroethanoicacid;TRIFLUOROACETETIC ACID;Trifluoroaceticacidbiolgrmincolorlessliq

    CAS No.:

    76-05-1

    Molecular Formula:

    C2HF3O2

    InChIKeys:

    DTQVDTLACAAQTR-UHFFFAOYSA-N

    Molecular Weight:

    114.02

    Exact Mass:

    114.02

    BRN:

    742035

    EC Number:

    200-929-3

    UNII:

    E5R8Z4G708

    ICSC Number:

    1673

    NSC Number:

    77366

    UN Number:

    2699

    TSCA:

    TSCA listed

    DSSTox ID:

    DTXSID9041578

    Color/Form:

    Colorless

    HScode:

    29159080

    Characteristics
    λmax:

    λ: 260 nm Amax: 0.9λ: 270 nm Amax: 0.10λ: 280 nm Amax: 0.05λ: 290 nm Amax: 0.04λ: 300 nm Amax: 0.03λ: 320 nm Amax: 0.025

    PSA:

    37.30000

    XLogP3:

    0.63330

    Appearance:

    Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent.

    Density:

    1.489 g/mL at 20 °C (lit.)

    Melting Point:

    -15.4 °C (lit.)

    Boiling Point:

    72.4 °C (lit.)

    Flash Point:

    -3ºC

    Refractive Index:

    n20/D1.3(lit.)

    Water Solubility:

    miscible

    Storage Conditions:

    2-8ºC

    Vapor Pressure:

    97.5 mm Hg ( 20 °C)

    Vapor Density:

    3.9 (vs air)

    Toxicity:

    LD50 i.v. in mice: 1200 mg/kg (Airaksinen, Tammisto)

    Odor:

    Sharp, pungent odor

    PH:

    1 (10g/l, H2O)

    PKA:

    -0.3(at 25℃)

    Henrys Law Constant:

    5.7×101mol/(m3Pa) at 25℃, Burkholder et al. (2019)

    Dissociation Constants:

    pKa = 0.3

    Experimental Properties:

    Strong, non-oxidizing acid|Hydroxyl radical reaction rate constant = 5.2X10-13 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Fumes in air. Soluble in water.

    Reactive Group:

    Acids, Carboxylic

    Reactivity Profile:

    Trifluoroacetic acid is a strong acid; attacks many metals [Handling Chemicals Safely 1980. p. 935]. A 30% solution of hydrogen peroxide in Trifluoroacetic acid is often used to destructively oxidize aromatic rings in preference to the side chains. Explosions have occurred, if the excess peroxide is not catalytically destroyed, prior to removal of solvent, [Tetrahedron Lett., 1977, 1703-1704]. The reduction of amides of Trifluoroacetic acid with lithium aluminum hydride are dangerous at all phases of the process, explosions have occurred, [Chem. Eng. News, 1955, 33, 1368].

    Physical Dangers:

    The vapour is heavier than air.

    Corrosivity:

    Corrosive

    Critical Temperature & Pressure:

    Store at +15°C to +25°C.

    Hazard Identification

    Classification of the substance or mixture

    Skin corrosion, Sub-category 1A

    Acute toxicity - Category 4, Inhalation

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H314 Causes severe skin burns and eye damage

    H332 Harmful if inhaled

    H412 Harmful to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P273 Avoid release to the environment.

    Response

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO contact with bases, oxidizing agents or reducing agents. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from strong bases, metals, oxidants and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    API,Intermediate

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    30

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    201-300

    About Echemi Pharmaceutical 

    Echemi’s philosophy is to seek for higher quality, to explore frontier area. The progress of human society, the extension of life expectancy, and the conquest of disease are all derived from the numerous businesses and individuals who have quietly dedicated themselves in the pharmaceutical industry. It’s the controlling of supply chain quality that ensures the efficacy. It’s the continuous exploration that promotes the development of the pharmaceutical industry and benefits more future generations. The pursuit of high quality requires all partners of Echemi Pharmaceutical to be screened, whether its certificate, qualification or scale. In the field of renewal, we will embrace all new changes and make more contributions to the development of pharmaceutical industry.

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    Advantage for Pharmaceutical 

    • Having been working in pharmaceutical field for more then 15 years, we have experienced regulatory team, quality control team, sourcing team, technical support team, and logistics team. And we are familiar with the regulatory requirements from different areas, can offer tailored service for our customers.

    • We have hundreds of strategic partners for APIs, intermediates, and custom synthesis. All of our partners are ready to support our customers with documents, and be audited.

    • We can offer custom synthesis for some new chemical structures and some materials which there are no reliable suppliers.

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    Product Category 

    We care for human and animal health and we are committed to creating a better social environment.

    •  Human API

    • Intermediate

    • Veterinary API

    • Agrochemical

    • Fine Chemical

    • Custom Synthesis



  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Trifluoroacetic acid

    5.00 G Mar 4, 2026
    India

    Trifluoroacetic acid

    1000.00 KG Oct 15, 2024
    Bangladesh

    trifluoroacetic acid

    15 MT Mar 10, 2026
    India

    Trifluoroacetic acid

    500 KG Apr 30, 2025
    United States

    Trifluoroacetic acid

    25 L May 11, 2026
    Russia

    trifluoroacetic acid

    100 L Nov 18, 2025
    Thailand

    Trifluoro acetic acid

    3 MT May 16, 2024
    India

    TRIFLUOROACETIC ACID

    5 MT Jan 5, 2024
    United States

    Trifluoroacetic acid Pharma Grade

    1 MT Sep 23, 2023
    Russia

    Trifluoroacetic acid

    50 KG Aug 1, 2023
    India

    5-Bromothiophene-2-carbaldehyde

    1.00 KG May 6, 2026
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