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Plecanatide CAS NO.467426-54-6

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CAS No.:

467426-54-6

Grade:

Research grade

Port:

SHANGHAI

Packaging:

0.001kg/Bottle

Price valid (until):

2020-12-31

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Hangzhou Go Top Peptide Biotech Co.,Ltd.

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

7 days

Qualification:

Main Products:

Pharmaceutical Peptide,Cosmetic peptide,Custom peptides,API polypeptide,Amino acids and derivatives,Peptide - Teriparatide

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Product Description
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Description

Product Name:Plecanatide
Synonyms:Plecanatide Impurtiy
CAS No.:467426-54-6
Catalog No.:GT-F009
Key Specification:
Appearance: White powder
Purity (HPLC) ≥95.0%
Acetate Content(HPLC): 5.0%~12.0%
Water Content (Karl Fischer) ≤10.0%
Package:
Vacuum-packed with aluminum foil bag or transparent bag. 500mg,1g, 10g,50g 100g per package with icebag. Or according to your request.
Product Detail
Plecanatide is a minimally absorbed agonist of guanylate cyclase C receptors in the intestine and is used for treatment of chronic constipation and irritable bowel syndrome. Plecanatide has not been linked to serum enzyme elevations during treatment or to episodes of clinically apparent liver injury.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
ECHEMI Editorial Reference

Plecanatide is an oral guanylate cyclase-C agonist that is being developed by Synergy Pharmaceuticals for the treatment of gastrointestinal disorders, such as chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). It is a synthetic analogue of human uroguanylin, a 16 amino acid peptide that regulates ion and fluid transport in the gastrointestinal tract. In January 2017, plecanatide received its first global approval in the USA for the treatment of adult patients with CIC. Plecanatide is undergoing phase III investigation in IBS-C.

Basic Info

Product Name:
Plecanatide

Other Name:
Plecanatide;ASN-ASP-GLU-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BOND CYS1&CYS3,CYS2&CYS4);Plecanatide Impurtiy;L-Leucine, L-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12),(7→15)-bis(disulfide);Plecanatide impurity;Plecanatide USP/EP/BP;Prikanatide;ATCH(1-39)

CAS No.:
467426-54-6

Molecular Formula:
C65H104N18O26S4

InChIKeys:
NSPHQWLKCGGCQR-DLJDZFDSSA-N

Molecular Weight:
1681.89

Color/Form:
White to off-white

Characteristics

Density:
1.47±0.1 g/cm3(Predicted)

Boiling Point:
2120.0±65.0 °C(Predicted)

PKA:
3.61±0.21(Predicted)
Seller Information

Business Type:
Manufactory

Main Products:
Pharmaceutical Peptide,Cosmetic peptide,Custom peptides,API polypeptide,Amino acids and derivatives,Peptide - Teriparatide

Location:
5th Floor, Building 1, No. 600 Yinhai Street, Xiasha Street

Payment Terms:
TT against copy of documents

Average lead Time:
7 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2014

Hangzhou Go Top Peptide Biotech , established in 2014, is a technology-based peptide company and a National High-tech Enterprise located in Hangzhou of China. It is also the governing unit of Peptide Branch of China Biochemical Pharmaceutical Industry Association.
The company currently has a peptide research center in Hangzhou, covering an area of 2,000m2 . There are two cooperation plants for peptide commercialization located in Shangyu and Anji of Zhejiang province. The peptide center has equipped with several complete peptide productions lines, including several large-scale peptide synthesizers and advanced imported HPLC systems with different sizes. We also have GMP standard clean laboratories to meet client’s special needs. The company has passed ISO9001:2015 certification.
At present, the company has developed more than 40 mature pharmaceutical peptides, with the annual production capacity up to 100 kilograms. With a total of 20,000 custom peptides so far, we can provide the one-stop peptide services from research scale (mg) - pilot scale - commercial production(KGs).

English web site https://www.gtpeptide.com
Products and Services
1.Custom peptide synthesis, such as Research peptide, Neoantigen peptide, Clinical peptide.
2.Pharmaceutical peptide development and production.
3.Peptide CRO and CDMO.
4. Cosmetic peptide and formulation development.
5. Special protected amino acids and small molecules.
6. Commercialized peptide library.
7. Technical support of new drug development.

SHELLY HU Director of sales 13735575465 sales1@gotopbio.com
Cindy Mei The sales manager 13588827304 sales3@gotopbio.com

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Plecanatide	10 MT	Oct 12, 2026

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Plecanatide CAS NO.467426-54-6

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SHELLY HU	Director of sales	13735575465	sales1@gotopbio.com
Cindy Mei	The sales manager	13588827304	sales3@gotopbio.com