 Home > Active Pharmaceutical Ingredients > Nervous System Drugs > Edaravone for Sale > Edarovone 99% Edarovone, Amyotrophic lateral sclerosis BAIYU

Edarovone 99% Edarovone, Amyotrophic lateral sclerosis BAIYU

Name: Edarovone 99% Edarovone, Amyotrophic lateral sclerosis BAIYU
Brand: BAIYU
SKU: pr2106071229
Price: 100 USD
Availability: InStock

GMP 2 Inquiries

Unit Price: Get Latest Price 

CAS No.:

89-25-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

BAIYU

Packaging:

please consult for info

Price valid (until):

2022-12-31

Contact Supplier

 Chat Now

BaiyuPharna (FDFs+API)

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

10 days

Qualification:

Main Products:

Edaravone API,Ropivacaine Mesylate,Ambroxol,Pantoprazole Sodium,Enoxaparin Sodium,Clindamycin Phosphate

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Edarovone

Currently Edarovone is under development, and estimated to market in the end of 2021, for more details, please feel free to email us at sales@baiyu.cn

ECHEMI Editorial Reference

Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
1-phenyl-3-methyl-5-pyrazolone appears as white to off-white powder or crystals. (NTP, 1992)|DryPowder
1-phenyl-3-methyl-5-pyrazolone appears as white to off-white powder or crystals. (NTP, 1992)|Edaravone is a pyrazolone that is 2,4-dihydro-3H-pyrazol-3-one which is substituted at positions 2 and 5 by phenyl and methyl groups, respectively. It has a role as a radical scavenger and an antioxidant.|Edaravone is a free radical scavenger approved in May, 2017 for the treatment of amyotrophic lateral scleorosis (ALS). Clinical studies showed that the treatment attenuated deterioration of the disease when compared to placebo. It has been previously investigated for the treatment of ischemic stroke, reperfusion Injury, and myocardial Infarction as it possesses antioxidant and anti-apoptotic properties. Being a low molecular weight molecule with good water and lipid-soluble properies, it is therapeutically advantageous in crossing the blood-brain barrier to mediate nootropic and neuroprotective effects. Oral formulation of edaravone is currently under development.|Edaravone is a free radical scavenger and neuroprotective agent used for therapy of amyotrophic lateral sclerosis. Edaravone is associated with a low rate of serum aminotransferase elevations during therapy but has not been linked to instances of clinically apparent, acute liver injury.|An antipyrine derivative that functions as a free radical scavenger and neuroprotective agent. It is used in the treatment of AMYOTROPHIC LATERAL SCLEROSIS and STROKE.

Certificates

Basic Info

Product Name:

Edaravone

Other Name:

3H-Pyrazol-3-one,2,4-dihydro-5-methyl-2-phenyl-;2-Pyrazolin-5-one,3-methyl-1-phenyl-;2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one;C.I. Developer 1;Developer Z;1-Phenyl-3-methyl-2-pyrazolin-5-one;1-Phenyl-3-methyl-5-pyrazolone;Norphenazone;3-Methyl-1-phenylpyrazolin-5-one;3-Methyl-1-phenyl-2-pyrazoline-5-one;3-Methyl-1-phenyl-5-pyrazolone;1-Phenyl-3-methyl-5-pyrazolinone;3-Methyl-1-phenyl-2-pyrazolin-5-one;Norantipyrine;MCI 186;Edaravone;1-Phenyl-3-methyl-5-oxopyrazole;5-Methyl-2-phenylpyrazol-3-one;3-Methyl-1-phenylpyrazol-5(4H)-one;Radicut;3-Methyl-1-phenyl-4,5-dihydropyrazol-5-one;NSC 12;Methylphenylpyrazolone;NSC 26139;NCI-C 03952;NSC 2629;Edarabone;3-Methyl-1-phenyl-1H-pyrazol-5-one;3-Methyl-1-phenyl-4,5-dihydropyrazole-5-one;1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-one;5-Methyl-2-phenyl-2H-pyrazol-3(4H)-one;3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one;5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one;3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one;Phenylmethyl pyrazolone;Radicava;4,5-Dihydro-3-methyl-5-oxo-1-phenylpyrazole;Edvaradone;3-Methyl-1-phenylpyrazole-5-one;5-Methyl-2-phenyl-2,4-dihydropyrazol-3-one;Edaravon;115566-83-1;12235-58-4;52224-17-6;62495-97-0;72134-66-8;206195-95-1

CAS No.:

89-25-8

Molecular Formula:

C10H10N2O

InChIKeys:

InChIKey=QELUYTUMUWHWMC-UHFFFAOYSA-N

Molecular Weight:

174.19900

Exact Mass:

174.20

EC Number:

201-891-0

NSC Number:

758622|26139|2629|12

DSSTox ID:

DTXSID9021130

Color/Form:

MONOCLINIC PRISMS FROM WATER|WHITE POWDER OR CRYSTALS

ATC Code:

N - Nervous system

HScode:

2933199090

Categories:

Nervous System Drugs

Characteristics

PSA:

32.67000

XLogP3:

1.3

Appearance:

1-phenyl-3-methyl-5-pyrazolone appears as white to off-white powder or crystals. (NTP, 1992)

Density:

1.12

Melting Point:

127 °C

Boiling Point:

287 °C @ Press: 105 Torr

Flash Point:

155.2ºC

Refractive Index:

1.606

Water Solubility:

H2O: 3 g/L (20 ºC)

Storage Conditions:

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protect

Vapor Pressure:

less than 0.01 mm Hg at 68 °F (NTP, 1992)

Toxicity:

LD50 orl-rat: 3500 mg/kg LONZA# 08FEB79

PKA:

7None

Dissociation Constants:

7.0

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Amides and Imides

Reactivity Profile:

Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

See More Edaravone Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Skin sensitization, Category 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H317 May cause an allergic skin reaction H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Edaravone Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Edaravone API,Ropivacaine Mesylate,Ambroxol,Pantoprazole Sodium,Enoxaparin Sodium,Clindamycin Phosphate

Location:
10th Floor, Building B7, Tianfu Life Science Park, Life Science Park, South Keyuan Road, Wuhou District, Chengdu, P.R.China

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
Above 1000

Year of Establishment:
2005

Baiyu , founded in 2005, is a pharmaceutical enterprise engaged in developing, manufacturing and distributing of high-quality pharmaceutical products and APIs. With about 1400 employees, Baiyu now has 6 subsidiaries including Golden Ginkgo Pharmaceutical Co., Ltd., Ginkgolide Pharmaceuticals Co., Ltd., Sunshine Ginkgo Agriculture Co.Ltd., Sichuan Yu Jian Pharmaceutical Co., Ltd. and Ginkgo Yukang Informatics Co.,Ltd., Ginkgo Yuda Pharmaceutical Co.,Ltd., et al.

Currently,we have 8 finished pharmaceutical products and 2 APIs on the market. Based on Quality-by-Design concept, our manufacturing sites strictly comply with cGMP and EU GMP. Ginkgolide injection, Enoxaparin sodium injection, Lansoprazole for injection are our main products.

Baiyu is growing fastly and has been awarded“National High-tech Enterprise”,“Sichuan Famous Brand”and“Enterprises with the most investment value in Chinese pharmaceutical industry”in 4 consecutive years.

The culture of kindness, Taiji and phoenix leads the way we behave and our vision is to constantly benefiting mankind to enjoy life-long well-being.

Baiyu provide CDMO service for FDFs & APIs as below

Dosage Form Production Lines Annual Capacity
Injection 8 650,000,000
Oral Solid 3 700,000,000
API & Intermediates 3 8,000 Kg
TCM Extraction 2 5,000,000 Kg

Our Advantages:

Quality by Design--Focusing on the conception of "intelligent, economic and sustainable" , we hired experienced talents from Germany designed manufacturing facilities for, pursuing internationally accredited manufacturing system that meets the requirements of US FDA, EMA, and NMPA.

Intelligent management with automatic production, digitized process

Our 4 Factories
•#1 Wenjiang •104667 m2；
•#2 Wenjiang •20000 m2；
•#3 Yuechi •130000 m2；
•#4 CDHT •53333 m2；

You are warmly welcomed to contact us for business cooperation.

sales@baiyu.cn
Chengdu Baiyu Pharmaceutical Co., Ltd.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Vietnam	Hair dye intermediates	1000 KG	Dec 4, 2024
Bangladesh	Butyl Acetate	1.00 KG	Nov 11, 2025

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one RC01272	/99	$1/KG EXW	Hangzhou Royalchem Co.,LTD	Inquiry
edaravone	Pharma Grade/99	$28/KG EXW	DAHAI BIOCHEM LTD	Inquiry
5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one	industrial Grade/98		Hangzhou KieRay Chem Co.,LTD	Inquiry
Edaravone	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
High Quality 99% Purity of 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one CAS NO 89-25-8 ISO 9001:2005 REACH Verified Producer	Industrial Grade/99		Shaanxi Dideu Medichem Co. Ltd	Inquiry

Hot Related Products



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.

Edarovone 99% Edarovone, Amyotrophic lateral sclerosis BAIYU

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Related Products

More Choices Find All Products for Sale 

Related Searches

More from this Seller

Hot Related Products