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Spiramycin tablets

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CAS No.:

8025-81-8

Packaging:

10 tablets*2/box

Price valid (until):

2022-01-12

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Topfond Pharmaceutical Co.,Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

API&intermediates

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Product Description
Seller Information
Inquiry History

Description

Product Detail

　　【Ingredients】

　　The main ingredient of this product is: Amikacin sulfate, its chemical name is: O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→4)-O-[6-amino- 6-Deoxy-α-D-Glucopyranosyl-(1→6)]-N3-(4-Amino-2-hydroxy-1-oxobutyl)-2-deoxy-L-streptamine sulfate salt. Excipients are: sodium dihydrogen phosphate, sodium acetate, sodium citrate, sodium bisulfite, water for injection.

　　Its chemical structure is:

　　Molecular formula: C22H43N5O13·1.8H2SO4; C22H43N5O13·2H2SO4

　　Molecular weight: 762.15;781.76

　　[Properties] This product is a colorless to slightly yellow clear liquid.

　　【Indications】

　　This product is suitable for Pseudomonas aeruginosa and some other Pseudomonas, Escherichia coli, Proteus, Klebsiella, Enterobacter, Serratia, Acinetobacter and other sensitive gram negative Severe infections caused by Bacillus and Staphylococcus (methicillin-sensitive strains), such as bacteremia or sepsis, bacterial endocarditis, lower respiratory tract infections, bone and joint infections, biliary tract infections, abdominal infections, and complicated urinary tract infections , Skin and soft tissue infections.

Basic Info

Product Name:

Spiramycin

Other Name:

Spiramycin;Foromacidin;Rovamycin;Provamycin;RP 5337;Espiramicin;Antibiotic 799;Selectomycin;Stomamycin;Sequamycin;NSC 55926;IL 5902;Rovamicina;Rovamycine;Spiramycins;1394-00-9;78355-64-3

CAS No.:

8025-81-8

InChIKeys:

ACTOXUHEUCPTEW-CEUOBAOPSA-N

Molecular Weight:

785.96

Exact Mass:

842.513977

EC Number:

232-429-6

DSSTox ID:

DTXSID9023594|DTXSID6045402

Color/Form:

Amorphous

ATC Code:

J - Antiinfectives for systemic use

HScode:

29419090

Categories:

Antibiotics

Characteristics

PSA:

195

XLogP3:

3.06

Appearance:

white to light yellow

Density:

1.2±0.1 g/cm3

Melting Point:

126-128 °C

Boiling Point:

914℃

Flash Point:

>110°(230°F)

Refractive Index:

1.550

Water Solubility:

soluble in methanol. Slightly soluble in water;ethanol: 50 mg/mL, clear to slightly hazy, light-yellow

Storage Conditions:

2-8°C

Vapor Pressure:

9.9X10-31 mm Hg at 25 °C (est)

Toxicity:

LD50 in rats (mg/kg): 9400 orally; 1000 s.c.; 170 i.v. (Sous)

Specific rotation:

D20 -80° (methanol)

PH:

Base

Henrys Law Constant:

Henry's Law constant = 9.0X10-35 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = 7.88; pKa2 = 9.28 (est)

Experimental Properties:

MW: 843.05. Crystals. MP: 134-137 °C. Specific optical rotation: -96 deg at 20 °C/D /Spiramycin I/|Crystals. MP: 140-143 °C. Specific optical rotation: -92.5 deg at 20 °C/D /Spiramycin I triacetate/|MW: 885.10. Crystals. MP: 130-133 °C. Specific optical rotation: -86 deg at 20 °C/D /Spiramycin II/|Crystals from cyclohexane. MP: 156-160 °C. Specific optical rotation: -98.4 deg at 20 °C/D /Spiramycin II diacetate/|MW: 899.11. Crystals. MP: 128-131 °C. Specific optical rotation: -83 deg at 20 °C/D /Spiramycin III/|Crystals from cyclohexane. MP: 140-142 °C. Specific optical rotation: -90.4 deg at 20 °C/D /Spiramycin III diacetate/

See More Spiramycin Properties 

Hazard Identification

Classification of the substance or mixture

Skin sensitization, Category 1

Eye irritation, Category 2

Respiratory sensitization, Category 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H317 May cause an allergic skin reaction H319 Causes serious eye irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H411 Toxic to aquatic life with long lasting effects
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P284 [In case of inadequate ventilation] wear respiratory protection. P273 Avoid release to the environment.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Spiramycin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
API&intermediates

Location:
No. 2 Guangming Road, Zhumadian, Henan Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A

Average lead Time:
15

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
101-200

Year of Establishment:
2003

Topfond Pharmaceutical Co.,Ltd is a leading Manufactory supplier of Azithromycin, Lincomycin hydrochloride monohydrate, Imiquimod based in Zhumadian, Henan, China. With a commitment to quality and customer satisfaction, Topfond Pharmaceutical Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Azithromycin, Lincomycin hydrochloride monohydrate, Imiquimod, which are available at competitive prices. Topfond Pharmaceutical Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
Peru	Spiramycin Raw Material Powder CAS 8025-81-8 bulk Spiramycin	25 KG	Nov 19, 2023
Vietnam	spiramycin	1000 KG	Jul 19, 2024
United States	Spiramycin	1 KG	Oct 1, 2024
Ecuador	Espiramicina adipato	0.50 KG	Jul 27, 2024
Vietnam	Spiramycin	4 TON	Jul 3, 2024

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Spiramycin tablets

Product Description

Seller Information