Vigabatrin
2 Inquiries
60643-86-9
Hyderabad
1kg
2022-01-01
Rabeprazole,Omeprazole,Silodosin,Levocetririzine
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite or almost white powder.
Vigabatrin is a second- generation anti- epileptic drug (AED), known under the proprietary brand name of Sabril® (Sanofi, Paris) in the UK and USA.
Vigabatrin, the gamma-vinyl derivative of GABA, is a new anticonvulsant reportedly effective in the treatment of intractable seizures unresponsive to currently available therapy. Mechanistically vigabatrin is a potent irreversible GABA aminotransferase inhibitor which modifies the enzyme's active-site by Michael addition. Other potential indications have been suggested for vigabatrin, including depression and schizophrenia.
ChEBI: A gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase
Vigabatrin, a 4-vinyl analog of GABA, produces its pharmacologicalaction by irreversibly blocking GABA catabolismcatalyzed by GABA-T as discussed earlier. It is marketedin Europe and Canada as an adjunctive treatment ofpatients with partial seizures, but it has yet to gain FDA approvalin the United States even after extensive clinical trials.The main concern with this drug is its ability to causea reversible visual field defect associated with retinal functionin the eyes.Basic Info-
Product Name:
VIGABATRIN
Other Name:[R,S]-4-AMINO-5-HEXENOIC ACID;VIGABATRIN;4-amino-5-hexenoicaci;4-amino-5-hexenoicacid;mdl71754;rmi71754;sabril;CPP109, CPP-109, CPP 109, RMI 71754, RMI71754, RMI-71754, MDL 71754, MDL-71754, MDL71754, VIGABATRIN, GAMMA-VINYL-GABA, SABRIL, SABRILEX
CAS No.:60643-86-9
Molecular Formula:C6H11NO2
InChIKeys:PJDFLNIOAUIZSL-UHFFFAOYSA-N
Molecular Weight:129.16
Exact Mass:129.16
EC Number:637-414-1
HScode:2922499990
Categories:
Characteristics-
PSA:
63.3
XLogP3:0.1
Appearance:Solid
Density:1.1±0.1 g/cm3
Melting Point:209°
Boiling Point:277.7±28.0 °C at 760 mmHg
Flash Point:9℃
Refractive Index:1.483
Water Solubility:9.66e+01 g/L
Storage Conditions:Desiccate at +4°C
Vapor Pressure:4.18X10-8 mm Hg at 25 °C (est)
Toxicity:LD50 i.p. in mice: >2500 mg/kg (Lscher)
PH:pH = 6.9 (1% aqueous solution)
PKA:4and 9.7
Critical Temperature & Pressure:Desiccate at +4°C
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Rabeprazole,Omeprazole,Silodosin,Levocetririzine
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Location:
Bhanu Enclave, No 302, above Hero Showroom, Sundar Nagar, Erragadda, Hyderabad, Telangana 500038
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A
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Average lead Time:
365 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2002
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
India
4-amino-5-hexenoic acid
100 KG Sep 30, 2025
India
Vigabatrin
100 KG Sep 30, 2025 Post an enquiry for this product
