782500-75-8
782500-75-8
kg
2022-01-09
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Description
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Seller Information
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DescriptionECHEMI Editorial Reference
Albiglutide is a long-acting GLP-1 receptor agonist and peptide-based pharmaceutical ingredient. It is a recombinant fusion protein consisting of a GLP-1 dimer linked to human albumin, with resistance to dipeptidyl peptidase-4 (DPP-4) degradation. Albiglutide is available as a pharmaceutical raw material for API research, development, analytical testing, and manufacturing.
Basic Info-
Product Name:
Albiglutide
Other Name:Albugon;Naliglutide;7-36-Glucagon-likepeptideI(8-glycine)(human),fusionproteinwith7-36-glucagon-likepeptideI(8-glycine)(human)fusionproteinwithserum;Gsk716155;7-36-Glucagon-likepeptideI[8-glycine](huMan),fusionproteinwith7-36-glucagon-likepeptideI[8-glycine](huMan)fusionproteinwithseruMalbuMin(huMan);AlbiglutideFragment
CAS No.:782500-75-8
Molecular Formula:C148H224N40O45
Categories:
Research-
Class:
GLP-1 receptor agonist (GLP-1 dimer fused to human albumin, long-acting)
Status:FDA-approved (Tanzeum 2014) — Withdrawn from market 2017 (commercial reasons)
Mechanism:A long-acting GLP-1 receptor agonist consisting of two copies of a modified human GLP-1 (7-36) sequence fused to human serum albumin via a glycine-glycine linker. The albumin fusion extends the half-life to ~5 days. Activates GLP-1R to enhance glucose-dependent insulin secretion and suppress glucagon.
Activity note:Albiglutide is a long-acting GLP-1R agonist. EC50 not publicly reported in standard databases; functional potency is lower than native GLP-1 due to albumin fusion.
Source:DrugBank: DB09030.
Clinical Development:FDA:Tanzeum (approved 2014-04-15)
References-
DrugBank:PubChem:Literature:Disclaimer:
Albiglutide was FDA-approved (Tanzeum) for type 2 diabetes but was withdrawn from the market in 2017 for commercial reasons, not safety. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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