Ubenimex China manufacture
58970-76-6
Yes
2026-11-14
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
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Product Description
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Seller Information
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DescriptionKeywords
Ubenimex
UBENIMEX
Ubenimex
Quick DetailsProName:Ubenimex China manufacture
CasNo:58970-76-6
Molecular Formula:C16H24N2O4
Appearance:White or off-white powder
Application:used for medicine
PackAge:Packaging according to customer requirements
Port:china port
ProductionCapacity:Metric Ton/Day
Purity:≥98.0%
Storage:Room temperature preservation
Transportation:by sea by air express
LimitNum:1 Kilogram
Superiority≥98.0%
Details
Appearance
White to off-white powder
Melting Point
225.3~225.6℃
Specific Rotation [α] 2 D 0
-15.5~ -18°(C=1 in 1N HCl)
Related Substance (TLC)
One spot
Related Substances
≤2.0%
Infrared detection
According with CP2010 standard
Identification
Reaction with CuSO4 in NaOH solution
Reaction with 20% Acetic acid, Ninhydrin and NaOH solution
pH
4.5-7.0
Residue on Ignition
≤0.10%
Heavy Metals
≤20ppm
Loss on drying
≤0.50%
Assay(T)
≥98.0%
Purity(HPLC)
≥98.0%
ECHEMI Editorial ReferenceBestatin is a natural, broad-spectrum, and competitive aminopeptidase inhibitor.
Ubenimex (also known as bestatin) is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.|Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Ubenimex competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Aminopeptidases has been implicated in the process of cell adhesion and invasion of tumor cells. Therefore, inhibiting aminopeptidases may partially attribute to the antitumor effect of ubenimex. This agent also activates T lymphocyte, macrophage and bone marrow stem cell as well as stimulates release of interleukin-1 and -2, thus further enhances its antitumor activity.Basic Info-
Product Name:
Bestatin
Other Name:L-Leucine,N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-;L-Leucine,N-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,[S-(R*,S*)]-;N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine;Bestatin;NK 421;Ubenimex;(-)-Bestatin;NSC 265489;339186-55-9
CAS No.:58970-76-6
Molecular Formula:C16H24N2O4
InChIKeys:InChIKey=VGGGPCQERPFHOB-RDBSUJKOSA-N
Molecular Weight:308.37300
Exact Mass:308.37
EC Number:261-529-2
UNII:I0J33N5627
DSSTox ID:DTXSID4048430
NCI Thesaurus Code:C1015
HScode:29242998
Categories:
Characteristics-
PSA:
112.65000
XLogP3:1.62400
Appearance:White crystalline powder
Density:1.197 g/cm3
Melting Point:234.5 °C
Boiling Point:604.7ºC at 760 mmHg
Flash Point:319.5ºC
Refractive Index:1.557
Water Solubility:Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq. NaOH (50 mM), ethanol (<1 mg/ml at 25°C), acetic acid, aq. HCl, and alkaline solution. Insoluble in ethyl acetate, benzene, hexane, and chloroform.
Storage Conditions:2-8ºC
Toxicity:LD50 in male, female mice, male, female rats (g/kg): 1.3, 1.9, 1.9, 2.1 s.c.; 0.19, 0.19, 0.90, 0.78 i.p.; >4.0, >4.0, >2.0, >2.0 orally (Sakakibara)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
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Location:
1613 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China.
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
7 days
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
11-50
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Year of Establishment:
2011
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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