 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid for Sale > Pemetrexed disodium INT-4

Pemetrexed disodium INT-4 buy - large image1

Pemetrexed disodium INT-4

Name: Pemetrexed disodium INT-4
Brand: shandong boyuan
SKU: pr2203221022
Price: 890 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

137281-39-1

Grade:

Industrial Grade

Content:

99%

Port:

beijing；shanghai

Brand:

shandong boyuan

Packaging:

25kg/Cardboard Drum

Price valid (until):

2024-07-31

Contact Supplier

 Chat Now

Shandong Boyuan Pharmaceutical Co., Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

 Visit Store

Product Description
Seller Information

Description

4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoicacid(intermediateofpemetrexed);4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-1H-PYMOL[2,3-D]PYRIMODIN-5-YL)ETHYL]BENZOICACID;4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoicAcid;4-[2-(2-Amino-4,7-dihydChemicalbookro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-BenzoicAcid;4-[2-（2-Amino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-yl）ethyl]benzoicacid;Pemetrexedreferencesubstance;Benzoicacid,4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-(9CI);PemetrexedIntermediateBenzoicAcid

InChI=1S/C15H14N4O3/c16-15-18-12-11(13(20)19-15)10(7-17-12)6-3-8-1-4-9(5-2-8)14(21)22/h1-2,4-5,7H,3,6H2,(H,21,22)(H4,16,17,18,19,20)

DMSO (Slightly), Methanol (Slightly, Heated)

Keep in dark place,Inert atmosphere,Room temperature

Introduction The boiling point of 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3]pyrimidin-5-yl)ethyl]benzoic acid is 609.2±65.0 degrees (under one atmosphere), with a density of 1.6. It appears as a white or gray-blue solid powder at room temperature and pressure. It can be used as a pharmaceutical intermediate and has certain solubility in dimethyl sulfoxide and methanol, but in Poor solubility in water. The synthesis method is to obtain 4-[2-(2-amino-4,7-dihydro- 4-Oxo-1H-pyrrole[2,3-d]pyrimidin-5-yl)ethyl]benzoate methyl ester, the ester product obtained can be obtained by hydrolyzing the ester group into carboxylic acid under alkaline conditions to obtain 4- [2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3]pyrimidin-5-yl)ethyl]benzoic acid.

The boiling point of 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3]pyrimidin-5-yl)ethyl]benzoic acid is 609.2±65.0 degrees ( Chemicalbook (under one atmosphere), with a density of 1.6. It appears as a white or gray-blue solid powder at room temperature and pressure. It can be used as a pharmaceutical intermediate and has certain solubility in dimethyl sulfoxide and methanol, but in Poor solubility in water.

Items	Specifications
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
Storage conditions	Keep in dark place,Inert atmosphere,Room temperature
InChI	InChI=1S/C15H14N4O3/c16-15-18-12-11(13(20)19-15)10(7-17-12)6-3-8-1-4-9(5-2-8)14(21)22/h1-2,4-5,7H,3,6H2,(H,21,22)(H4,16,17,18,19,20)

Shop Pemetrexed disodium INT-4-Detailed Image 1

Shop Pemetrexed disodium INT-4-Detailed Image 2

Shop Pemetrexed disodium INT-4-Detailed Image 3

Shop Pemetrexed disodium INT-4-Detailed Image 4

Basic Info

Product Name:

4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid

Other Name:

Benzoic acid,4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-;Benzoic acid,4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-;1H-Pyrrolo[2,3-d]pyrimidine,benzoic acid deriv.;4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid;Pemetrexed acid

CAS No.:

137281-39-1

Molecular Formula:

C15H14N4O3

InChIKeys:

InChIKey=AIZPFZIKHIJCQX-UHFFFAOYSA-N

Molecular Weight:

298.29666

Exact Mass:

298.30

EC Number:

429-790-9

UNII:

JBZ211669I

DSSTox ID:

DTXSID80430861

HScode:

29335990

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

121

XLogP3:

Appearance:

Pale Pink Solid

Density:

1.55±0.1 g/cm3(Predicted)

Melting Point:

>270°C (dec.)

Boiling Point:

609.2°C at 760 mmHg

Flash Point:

322.223ºC

Refractive Index:

1.746

Storage Conditions:

-20°C Freezer

Vapor Pressure:

0mmHg at 25°C

See More 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Carcinogenicity, Category 2

Reproductive toxicity, Category 1A

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H351 Suspected of causing cancer H360 May damage fertility or the unborn child
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

Location:
NO.28 SangYuan Rd,JinanCity,ShanDong Province,China

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
1

Total Annual Revenue:
$50 million-$100 million

Total Employees:
501-1000

Year of Establishment:
2005
Country Product Purchase Quantity Date Posted

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 137281-39-1 Pemetrexed intermediate white powder	/	Wuxi Taxus Pharmaceutical Co.,Ltd	Inquiry
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid	/99.00	HANGZHOU LEAP CHEM CO., LTD.	Inquiry
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid	industrial Grade/98	Hangzhou KieRay Chem Co.,LTD	Inquiry
Pemetrexed disodium Intermediate 99% GMP 99% White to Light Yellow	Pharmaceutical Grade/99	BrightGene Health Technology Co., Ltd	Inquiry