Isoniazid CAS54-85-3 with 100% Safe Delivery USA UK EU Canada Mexico Australia
ISO 3 Inquiries
54-85-3
0%
100g;1kg;25g
2022-12-31
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate
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Product Description
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Seller Information
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Inquiry History
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Description
Product description:It is mainly used for various types of pulmonary tuberculosis, tuberculous meningitis and other extrapulmonary tuberculosis. Often need to be combined with other antituberculosis drugs.Melting point 171-173 °C (lit.) Boiling point 251.97°C (rough estimate) density 1.2620 (rough estimate) refractive index 1.6910 (estimate) Fp >250°C storage temp. 2-8°C solubility 125g/l form Crystals or Crystalline Powder pka pKa 2.00/3.60/10.8(H2O) (Uncertain) color White or colorless 
Packing
· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
Delivery- ≤50kg, Express delivery recommended, usually called as DDU service;
- ≤500kg,Air shipping recommended, usually called as CIF service;
- >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
- For high value products, please select air shipping and express delivery for safety.
SHANDONG LOOK CHEMICAL CO.LTD, a new chemical enterprise in researching, manufacturing and supplying of chemicals located in beautiful "Spring City"-Jinan.Our company mainly working on the researching new-born APIs, intermediate ( especially Carbohydrate derivatives series). Meanwhile, we made huge breakthrough in industries of food, feed additives, cosmetics ,dye and industrial chemicals. Our company enjoyed great reputation both domestic and abroad under the belief of "Integrity management,Quality controlling and Customer orientation".
We had been cooperated with NingXia University and Shandong University on more than ten projects for years and which had been in mass production on the market. We now have more than 80 people in our team and built research center in Jinan and Ningxia. Our manufacturing site allocated in chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly complying with ISO9001 and ISO 2000 standard in manufacturing process, our lab and workshop tightly in accordance with GMP standard.Our products best selling in Europe, South and North America,Asia pacific area and Africa. We sincerely welcome new and regular customers around the world visit us for business negotiation.
FAQ- DO YOU ACCEPT SAMPLE ORDER?
We accept sample orders. We will make samples before mass production, and after sample approved, we'll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
2.HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
3.WHAT'S YOUR MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
4.DO YOU SUPPLY PRODUCT REPORT?
Yes. We'll give you product analysis report before shipping.
5.IS THERE A DISCOUNT?
Different quantity has different discount.
Our Advantage
10 Years Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour serviceQuick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.ECHEMI Editorial ReferenceIsoniazid is an antibacterial agent used primarily as a tuberculostatic.Target: AntibacterialIsoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG [1]. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH complex. This complex binds tightly to the enoyl-acyl carrier protein reductase known as InhA, thereby blocking the natural enoyl-AcpM substrate and the action of fatty acid synthase. This pro
Isoniazid appears as odorless colorless or white crystals or white crystalline powder. Taste is slightly sweet at first and then bitter. pH (1% aqueous solution) 5.5-6.5. pH (5% aqueous solution) 6-8. (NTP, 1992)|Solid|WHITE CRYSTALLINE ODOURLESS POWDER.
Isoniazid appears as odorless colorless or white crystals or white crystalline powder. Taste is slightly sweet at first and then bitter. pH (1% aqueous solution) 5.5-6.5. pH (5% aqueous solution) 6-8. (NTP, 1992)|Isoniazide is a carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine. It has a role as an antitubercular agent and a drug allergen. It derives from an isonicotinic acid.|Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.|Isoniazid is an Antimycobacterial.|Isoniazid is the most reliable and most commonly used medication for tuberculosis. Isoniazid therapy is often associated with minor, transient and asymptomatic elevations in serum aminotransferase levels but, more importantly, isoniazid is a well known cause of acute clinically apparent liver injury which can be severe and is sometimes fatal.|Isoniazid is a synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due to decreased bacterial wall penetration. (NCI04)CertificatesBasic Info-
Product Name:
Isoniazid
Other Name:4-Pyridinecarboxylic acid,hydrazide;Isonicotinic acid hydrazide;FSR 3;5015 R.P.;Armazide;Cotinazin;Ditubin;Dinacrin;Ertuban;Eutizon;HIA;Hidrasonil;Hycozid;Hydrazid;Isidrina;Isobicina;Isocotin;Isolyn;Isonex;Isoniazid;Isoniazide;Isonicid;Isonico;Isonicotan;Isonicotinoylhydrazine;Isonidrin;Isonilex;Isonindon;Isonizide;Isotebezid;Isozide;Isozyd;Laniazid;Mybasan;Neoteben;Neumandin;Nevin;Niadrin;Nicetal;Nicizina;Niconyl;Nicotibina;Nicozide;Nidaton;Nikozid;Niplen;Nydrazid;Nyscozid;Pelazid;Preparation 6424;Pycazide;Pyricidin;Pyrizidin;Raumanon;Retozide;Rimifon;Robisellin;RU-EF-Tb;Sauterazid;TB-Vis;Tebecid;Teebaconin;Tekazin;Tibinide;Tibizide;Tisin;Tisiodrazida;Tizide;Tubazid;Tubazide;Tubicon;Tubomel;Tyvid;Unicozyde;Vazadrine;Vederon;Zinadon;Zonazide;Isonicotinic hydrazide;Isonicotinoyl hydrazide;Rimiphone;Isoniazid SA;Isocid;Cedin;Neoxin;Rimitsid;Hyzyd;Nitadon;Tubilysin;Tubeco;Atcotibine;NSC 9659;Nidrazid;Armazid;Zidafimia;Hidranizil;T.B. Razide;Eralon;Nicotisan;Rimicid;4-Pyridylcarbonylhydrazide;Isonicotinohydrazide;4-Pyridinecarbonylhydrazine;4-Pyridinecarboxylic hydrazide;Isozin;4-(Hydrazinocarbonyl)pyridine;[(4-Pyridinylcarbonyl)oxy]hydrazine;Dianicotyl;GINK;Pyridine-4-carbohydrazide;Mayambutol;Lafepe;Isonicotinic acid hydrazyde;Isocaldin;Isokin;Solonex;Ipcazide;7640-37-1;37271-10-6;41466-07-3;62229-51-0
CAS No.:54-85-3
Molecular Formula:C6H7N3O
InChIKeys:InChIKey=QRXWMOHMRWLFEY-UHFFFAOYSA-N
Molecular Weight:137.14
Exact Mass:137.14
BRN:119374
EC Number:200-214-6
UNII:V83O1VOZ8L
ICSC Number:1258
NSC Number:757078|9659
DSSTox ID:DTXSID8020755
NCI Thesaurus Code:C600
Color/Form:COLORLESS OR WHITE CRYSTALS, OR A WHITE, CRYSTALLINE POWDER|Crystals from alcohol
ATC Code:QI01AN01|J04AC01|J - Antiinfectives for systemic use
HScode:2933399090
Categories:
Characteristics-
PSA:
68
XLogP3:-0.7
Appearance:White or colorless Crystals or Crystalline Powder
Density:1.420 g/cm3
Melting Point:171.4 °C
Flash Point:>250°C
Refractive Index:1.584
Water Solubility:H2O: 14 g/100 mL (25 ºC)
Storage Conditions:Refrigerator
Vapor Pressure:4.6X10-5 mm Hg at 25 deg C /Estimated/
Toxicity:LD50 in mice (mg/kg): 151 i.p., 149 i.v. (Jenney, Pfeiffer)
PH:pH of a 1% aqueous solution 5.5 to 6.5
PKA:1.82(at 20 °C)
Henrys Law Constant:Henry's Law constant = 1.2X10-14 atm-cu m/mole at 25 °C /Estimated/
Dissociation Constants:1.82 (at 20 °C)|pK1= 1.75; pK2= 3.57; pK3= 10.75
Collision Cross Section:125.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Can react as weak acid or weak base; can be hydrolyzed to release hydrazine; lysed at hydrazine moiety by redox reactions.|Aqueous solutions may be sterilized at 120 °C for 30 minutes.|An equimolecular salt produced by dissolving the components in hot dil alc, followed by cooling and evapn ... MW: 290.27. Yellow crystals from methanol or ethanol; mp 142-144 °C. Sparingly soluble in water, uv max 272, 303 nm (E(1%)(1 cm) 550, 445). /4-Aminosalicylate/|MW: 231.23. Crystals, dec 187-189 °C /Methanesulfonate/|For more Other Experimental Properties (Complete) data for ISONIAZID (7 total), please visit the HSDB record page.
Air and Water Reactions:Sensitive to air and light. Absorbs insignificant amounts of moisture at 77°F at relative humidities up to approximately 90%. Water soluble. Dust can be explosive when suspended in air at specific concentrations.
Reactive Group:Amides and Imides
Reactivity Profile:ISONIAZID is incompatible with chloral, aldehydes, iodine, hypochlorites and ferric salts. It is also incompatible with oxidizers. It may react with sugars and ketones. It can react as a weak acid or a weak base. It can be decomposed by oxidative and reductive reactions. (NTP, 1992)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Cool. Well closed.Store below 40 deg C (104 deg C), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by manufacturer. Store in a tight, light-resistant container. Protect from freezing. NOTE: Crystallization may occur at low temperatures. Upon warming to room temperature, the crystals will redissolve.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate
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Location:
hisense intelligence valley,no 2116,of phoenix road
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
7 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
South Korea
Isoniazid
1 KG Sep 7, 2026 
Russia
Isoniazid CAS54-85-3 with 100% Safe Delivery USA UK EU Canada Mexico Australia
100 G Oct 26, 2024 
India
Isoniazid
200 KG Mar 11, 2024 Post an enquiry for this product
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