Oxytocin 99%

Oxytocin, also known as oxytocin, is a uterine contractile drug, which can be extracted from the posterior pituitary of animals or synthesized chemically. The chemical synthetic product does not contain vasopressin and has no pressor effect. It has a selective excitatory effect on uterine smooth muscle and strengthens its contraction. The parturient uterus is most sensitive to oxytocin (increased estrogen secretion), the immature uterus is not reactive to this product, and the uterus in the early or middle trimester of pregnancy has low reactivity to oxytocin, It increased gradually in the late pregnancy and reached the highest before labor. Low dose can strengthen the rhythmic contraction of the smooth muscle at the bottom of the uterus, strengthen its contractility and accelerate the contraction frequency. The contraction nature is similar to natural delivery, and maintain polarity and symmetry. Therefore, it is clinically used to induce labor. Large dose makes the uterine muscle contract in a tonic way. It is clinically used to compress the blood vessels between muscle fibers, prevent postpartum hemorrhage and incomplete postpartum involution, promote lactation, shrink the breast duct and promote the discharge of milk from the breast, but it can not increase the secretion of milk, but can only promote the discharge of milk. It should be noted that the dosage and dropping speed should be strictly controlled when used for labor induction or induction, so as not to cause ankylosing uterine contraction, fetal asphyxia or uterine rupture. It is forbidden when there is cephalic basin, chemical book is not balanced, fetal position is incorrect or other birth canal abnormalities, poor uterine contraction, cesarean section history and more than 3 times of pregnant women. Oxytocin preparations isolated from the pituitary of cattle and pigs occasionally cause allergic reactions. Too fast intravenous drip can cause mild vasodilation and decrease of blood pressure. The fastest dropping speed shall not exceed 40 ~ 60 drops per minute. A slightly larger dose is also used for postpartum hemorrhage, poor placenta, etc. In recent years, it has been found that this product has a good effect on Pulmonary Hemoptysis and gastrointestinal function relaxation after vagotomy or abdominal surgery. Oral administration is ineffective. It is easy to be destroyed by digestive juice, but it can be absorbed by oral mucosa. Intravenous drip of 0.01iu can cause uterine physiological contraction (rhythmic, polar and symmetrical) within 1 ~ 3 minutes. The retention time is short, and the half-life is only 2.5 ~ 3 minutes. High dose makes uterine muscle tonic contraction. It has synergistic effect with prostaglandins. Oxytocin is often combined with ergot preparation to treat postpartum hemorrhage; Inevitable abortion; It is mainly used for induced labor in late pregnancy and delayed labor caused by uterine atony during labor; For oxytocin sensitivity test; For oxytocin provocation test; Assist in postpartum milk excretion; Hemoptysis; Postoperative gastrointestinal peristalsis was delayed.