Bulk Cyclopeptide Antimicrobial Agents Daptomycin Powder CAS 103060-53-3 Daptomycin
HALAL ISO FDA 7 Inquiries
103060-53-3
Pharmaceutical Grade
0%
ZB
Boil Bag
2022-12-31
Herb Extracts,Cosmetic raw materails,API
-
Product Description
-
Seller Information
-
Inquiry History
-
Description
Product Name: Daptomycin
CAS: 103060-53-3
MF: C72H101N17O26
MW: 1620.67
EINECS: 600-389-2
Melting point:202-204°C
Boiling point :2078.2±65.0 °C
density :1.45±0.1 g/cm3
storage temp. :Sealed in dry
Form :powder
Daptomycin is the first entry of a new class of cyclic lipopeptide antibiotics that disrupts multiple aspects of bacterial membrane function including disruption of membrane potential and amino acid transport, inhibition of lipoteichoic acid synthesis and inhibition of peptidoglycan synthesis. It is indicated for the treatment of complicated skin and skinstructure infections (cSSSI) caused by a range of Gram-positive bacteria. This is distinct from previous classes of antibiotics that inhibit bacterial cell wall biosynthesis, bacterial DNA replication, and folate coenzyme biosynthesis. Due to this unique mechanism, cross-resistance has not been noted with any other class of antibiotics. It is produced by the fermentation of Streptomyces roseporus.
It is a pharmaceutical intermediate for the treatment of concurrent skin and skin structure infections caused by some gram-positive and sensitive strains.
Cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.
CertificatesBasic Info-
Product Name:
Daptomycin
Other Name:daptomycin;CUBICIN DAPTOMYCIN;Cidecin;Cubicin;Ly-146032;N-(N-Decanoyl-L-Trp-D-Asn-L-Asp-)cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-];N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-]
CAS No.:103060-53-3
Molecular Formula:C72H101N17O26
InChIKeys:DOAKLVKFURWEDJ-OFNKPWESSA-N
Molecular Weight:1620.68
Exact Mass:1619.710327
EC Number:1533716-785-6
DSSTox ID:DTXSID1041009
ATC Code:J01XX09|J - Antiinfectives for systemic use
HScode:29419090
Categories:
Characteristics-
PSA:
702
XLogP3:0.88280
Appearance:colorless to faint yellow
Density:1.45±0.1 g/cm3(Predicted)
Melting Point:202-204°C
Boiling Point:2078.2°C at 760 mmHg
Flash Point:87℃
Refractive Index:1.638
Water Solubility:methanol: soluble5mg/mL
Storage Conditions:Store at -20°C
Vapor Pressure:0mmHg at 25°C
Toxicity:LD50 i.v. in mice: 600 mg/kg (Debono)
Collision Cross Section:416.8 Ų [M+2H-H2O]2+
Hazard IdentificationClassification of the substance or mixture
Specific target organ toxicity â repeated exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P319 Get medical help if you feel unwell.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Herb Extracts,Cosmetic raw materails,API
-
Location:
1403,Jinye B Block
-
Payment Terms:
TT against copy of documents
-
Average lead Time:
8
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
11-50
-
Year of Establishment:
2015
-
-
Inquiry History7 Inquiries
Country Product Purchase Quantity Date Posted 
Vietnam
Daptomycin
500 KG Apr 30, 2024 
India
Daptomycin
1.00 KG Mar 8, 2024
India
Daptomycin
1.00 KG Mar 7, 2024
India
Upadacitinib
10.00 KG Mar 6, 2024
India
Ripretinib
10.00 KG Mar 6, 2024
India
URSODEOXYCHOLIC ACID
10.00 KG Mar 6, 2024
India
Acarbose
10.00 KG Mar 6, 2024 Post an enquiry for this product