Anti-Acne Cosmetic Material 99% Tretinoin Powder Vitamin a Acid CAS: 302-79-4 Tretinoin
HALAL KOSHER ISO FDA 8 Inquiries
302-79-4
Pharmaceutical Grade, Food Grade, Cos
0%
Foil Bag
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Product name:Vitamin A Acid Other Names: Retinoic Acid
CAS No.:302-79-4 Appearance: Yellow crystalline powder
EINECS No.206-129-0 Molecular Formula C20H28O2
Grade Standard:Food Grade, Medicine Grade, Cosmetic Grade Purity: 99%
Usage:Pharmaceuticals, for treatment of acne Appearance: Yellow crystalline powder
Loss on drying::Not more than 0.5% Brand TGY
Heavy metals::Not more than 0.002% Identification:: Conforms 
Tretinoin , also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic
leukemia. For acne, it is applied to the skin as a cream or ointment. For leukemia, it is taken by mouth for up to three months.
Common side effects when used by mouth include shortness of breath, headache, numbness, depression, skin dryness, itchiness,
hair loss, vomiting, muscle pains, and vision changes. Other severe side effects include high white blood cell counts and blood clots.
When used as a cream side effects include skin redness, peeling, and sun sensitivity. Use during pregnancy is known to harm the
baby. It is in a retinoid family of medications.Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.
Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene.
This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia.
ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.
Items
Specification
Results
Description
Yellow crystalline powder
Yellow crystalline powder
Identification
Complies
Complies
Organic Volatile Impurity
Complies
Complies
Loss on drying
≤0.5%
0.18%
residue on ignition
≤0.1%
0.05%
Heavy Metals
≤0.002%
0.001%
Limit of Tretinoin
≤0.1%
0.18%
Assay
98.0~102.0%
99.4%
CONCLUSION: CONFORM TO THE SPECIFICATION OF USP30.
1. Tretinoin is a drug commonly used to treat acne vulgaris and keratosis pilaris.
2. Tretinoin is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.
3. Tretinoin can stimulate skin growth and keep epidermic normal.
4. Tretinoin can slow down the skin aging process for solarization, remove tiny wrinkles.
5. Tretinoin can reduce skin roughness, so the skin will become ruddy.
6. Tretinoin is widely applied in the pharmaceutical field, mainly used for the cure of dermatoses like acne, ichthyosis, and psoriasis abnormal, etc.
7 . Tretinoin can be made into tretinoin or retinoic acid cream to cure acne or other unhealthy skin.
8. Tretinoin is used for skin keratinocytes-resistant drugs and cell-induced differentiation drugs. metic products in Europe and the United States were welcomed by the decades.
CertificatesBasic Info-
Product Name:
Retinoic acid
Other Name:Retinoic acid;Retinoic acid,all-trans-;Vitamin A acid;Tretinoin;trans-Retinoic acid;2,4,6,8-Nonatetraenoic acid,3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-,(all-E)-;all-trans-Vitamin A acid;Vitamin A acid,all-trans-;Vitamin A1 acid,all-trans-;3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid;β-Retinoic acid;(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid;all-trans-Tretinoin;all-(E)-Retinoic acid;Tretin M;all-trans-β-Retinoic acid;Ro 1-5488;Retin A;AGN 100335;Aberel;all-trans-Retinoic acid;Vesanoid;ATRA;Renova;Atragen;Vesnaroid;Epi-Aberel;Cordes Vas;Dermairol;Aknoten;Airol;NSC 122578;Eudyna;Retacnyl;NSC 122758;7005-78-9;56573-65-0;187175-63-9
CAS No.:302-79-4
Molecular Formula:C20H28O2
InChIKeys:InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N
Molecular Weight:300.44
Exact Mass:300.44
BRN:2057223
EC Number:206-129-0
HScode:2916209090
Categories:
Characteristics-
PSA:
37.3
XLogP3:6.3
Appearance:yellow powder
Density:1.0±0.1 g/cm3
Melting Point:180-182 °C
Boiling Point:462.8°C at 760 mmHg
Flash Point:350.6±11.0 °C
Refractive Index:1.556
Water Solubility:H2O: insoluble ;soluble in ether; slightly soluble in chloroform.
Storage Conditions:2-8°C
Vapor Pressure:2.4X10-7 mm Hg @ 25 deg C /Estimated/
Toxicity:LD50 (10 day) in mice, rats (mg/kg): 790, 790 i.p.; 2200, 2000 orally (Kamm)
Odor:Floral odor (powder form)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Reproductive toxicity, Category 1B
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H315 Causes skin irritation
H360 May damage fertility or the unborn child
H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History8 Inquiries
Country Product Purchase Quantity Date Posted 
India
RETINOIC ACID
300 KG Jun 29, 2026 
Egypt
Retinoic acid
1 KG Dec 2, 2023 
Philippines
Vitamins Tretinoin Vitamin A Acid Powder
5 G Sep 21, 2023 
Switzerland
Retinoic acid
100 G Feb 5, 2026 
Saudi Arabia
Retinoic acid
50 G Dec 4, 2023 
Finland
retinoic acid
1 KG Mar 19, 2026 
Germany
Tretinoin
1000 MG Dec 8, 2025
Egypt
Retinoic acid
50 G Dec 4, 2023 Post an enquiry for this product