Bulk API Nifedipine Powder Best Price CAS 21829-25-4
3 Inquiries
21829-25-4
Pharmaceutical Grade
99%
XAZB
Foil Bag
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Product Description
Nifedipine is also called the nifedipine, the flat, benzene, pyridine, nitrate is a kind of two hydrogen pyridine class calcium antagonists, inhibit myocardial and vascular smooth muscle of Ca2 + uptake, expansion of coronary artery, increase coronary blood flow, improve myocardial ischemia tolerance, expands around the small artery at the same time, reduce the peripheral vascular resistance, alleviate coronary artery spasm, increase the coronary flow, improve myocardial ischemia, making the blood pressure to drop. Low dose dilation of coronary artery does not affect blood pressure. For the prevention and treatment of coronary heart disease angina, no adverse effects on respiratory function, especially for coronary artery spasm caused by angina and suffering from respiratory obstructive disease angina, the best effect, the effect is better than receptor blockers. It is also suitable for all types of hypertension, including severe and refractory hypertension. For the treatment of refractory congestive heart failure, this product can be taken for a long time. It is also used for the treatment of primary pulmonary hypertension, diffuse esophageal spasm and bronchial asthma, duodenal bulbous ulcer, urethral obstruction, sports asthma, achalasia of cardia and so on.
Nifedipine has a certain selectivity to vascular smooth muscle and a weak direct negative myodynamic effect and denaturation effect on the heart. Therefore, systemic administration of nifedipine does not cause slow heart rate, but shows an increase in heart rate reflex.
FunctionsLong-acting coronary dilators. This product can increase coronary blood flow and reduce myocardial oxygen consumption. For acute and chronic coronary insufficiency, especially angina and myocardial infarction.
Basic Info-
Product Name:
Nifedipine
Other Name:3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-,dimethyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-,dimethyl ester;Nifedipine;BAY-a 1040;4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine;Adalat;BAY 1040;2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine;Corynphar;Corinfar;Procardia;Fenihidine;Glopir;TN 873R;Cordafen;2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester;Cordaflex;Niphedipine;Dimethyl 4-(o-Nitrophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate;Procardia XL;Nifelate;Sepamit R;Adalat CC;Nifelan;Nifedipine retard;UV-ENP 349PINA;Macorel;Duranifin;Adalat 10;Nifangin;Anpine;Dignokonstant;Zenusin;Adalat LA;Nifedipres;Adalat GITS 30;Fedcor Retard;Alonix S;Fedipin;Coracten;Vasdalat;Fenamon SR;Adalat 20;Nifedirex LP;Nifelat;Ecodipin;Fenamon;Pidilat;Adalat CR;Nifedin;Nifedine;Hadipine;Cordalat;Myogard;Adalat LP;Nifecard;Adalat 5;Calcilat;Nifidine;Adalat GITS;Tibricol;Nificard;Osmo-Adalat;Chronadalate LP;Sepamit;Nyefax;Nifebene;Vasofed;Tensopin;Alpha-Nifedipine Retard;Cordipin;Corotrend;Ecodipin E;Nifelat Q;Adalat FT;Adapine;Citilat;Alonix;Cardifen;Dilcor;Normadil;Adalat PA;Dipinkor;Nifdemin;Adalat Oros;Nicardia;Apo-Nifed;Fedcor;Adalate;101539-70-2;101554-38-5;11104-22-6
CAS No.:21829-25-4
Molecular Formula:C17H18N2O6
InChIKeys:InChIKey=HYIMSNHJOBLJNT-UHFFFAOYSA-N
Molecular Weight:346.34
Exact Mass:346.33
EC Number:244-598-3
UNII:I9ZF7L6G2L
NSC Number:757242
DSSTox ID:DTXSID2025715
NCI Thesaurus Code:C29290
Color/Form:Yellow crystals
ATC Code:C08CA05|C - Cardiovascular system
HScode:29333990
Categories:
Characteristics-
PSA:
110
XLogP3:2
Appearance:yellow powder
Density:1.2109 (rough estimate)
Melting Point:172-174 °C
Boiling Point:475.3ºC at 760 mmHg
Flash Point:241.2ºC
Refractive Index:1.584
Water Solubility:H2O: <0.1 g/100 mL at 19.5 ºC;DMSO: soluble
Storage Conditions:2-8°C
Vapor Pressure:2.6X10-8 mm Hg at 25 deg C
Toxicity:Oral-rat LD50: 1022 mg/kg; Oral-Mouse LD50: 310 mg/kg
Flammability characteristics:Combustion produces toxic nitrogen oxide fumes; medicinal side effects: low blood pressure, cardiomyopathy, local blood flow disorders, hyperglycemia, psychosis
Henrys Law Constant:Henry's Law constant = 7.3X10-14 atm-cu m/mol at 25 °C (est)
Collision Cross Section:169.4 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Very light sensitive in solution|Hydroxyl radical reaction rate constant = 1.1X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Aqueous solutions are very sensitive to light. (NTP, 1992). Insoluble in water.
Reactive Group:Amines, Phosphines, and Pyridines
Reactivity Profile:NIFEDIPINE is sensitive to light.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Nifedipine liquid-filled capsules should be protected from light and moisture and stored in tight, light-resistant containers at a temperature of 15-25 deg C, and extended-release tablets of the drug should be protected from light and moisture and stored in tight, light-resistant containers at a temperature less than 30 deg C.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
Germany
Nifedipine
160 KG Dec 31, 2025 
Egypt
Bulk API Nifedipine Powder Best Price
1 KG Sep 17, 2023
Egypt
Nifidipine
1 KG May 12, 2024 Post an enquiry for this product
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