Butyl 4-aminobenzoate
94-25-7
Cosmetics Grade
99%
Shanghai
Pharma;Conutrix
25kg/Cardboard Drum
Yes
2022-12-31
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceButamben is a long-duration local anesthetic used for the treatment of chronic pain.
N-butyl-p-aminobenzoate is a yellow powder. Insoluble in water. (NTP, 1992)
N-butyl-p-aminobenzoate is a yellow powder. Insoluble in water. (NTP, 1992)|Butamben is an amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders. It has a role as a local anaesthetic. It is a benzoate ester, a substituted aniline, an amino acid ester and a primary amino compound. It derives from a 4-aminobenzoic acid and a butan-1-ol. It is a conjugate base of a butamben(1+).|Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben was considered of low usability as it is only suitable to be used as a topical anesthesia. This belief changed with the introduction of epidural suspensions of butamben. All butamben-containing products were removed from the market under the belief that it is unsafe or ineffective.Basic Info-
Product Name:
Butyl 4-aminobenzoate
Other Name:Benzoic acid,4-amino-,butyl ester;Benzoic acid,p-amino-,butyl ester;Butamben;Butesin;Butoform;Butyl Keloform;Planoform;Scuroform;Scuroforme;Butyl p-aminobenzoate;Butyl 4-aminobenzoate;n-Butyl p-aminobenzoate;p-Aminobenzoic acid butyl ester;4-(Butoxycarbonyl)aniline;Butylcaine;Butesine;p-Aminobenzoic acid n-butyl ester;n-Butyl 4-aminobenzoate;Butsein;NSC 128464;Butambene;4-Aminobenzoic acid butyl ester;Hemoride
CAS No.:94-25-7
Molecular Formula:C11H15NO2
InChIKeys:InChIKey=IUWVALYLNVXWKX-UHFFFAOYSA-N
Molecular Weight:193.24
Exact Mass:193.24
EC Number:202-317-1
UNII:EFW857872Q
NSC Number:757433|128464
DSSTox ID:DTXSID7022417
Color/Form:Crystals from alc|White powder|White, amorphous powder
HScode:2922499990
Categories:
Characteristics-
PSA:
52.3
XLogP3:2.9
Appearance:N-butyl-p-aminobenzoate is a yellow powder. Insoluble in water. (NTP, 1992)
Density:1.1±0.1 g/cm3
Melting Point:58 °C
Boiling Point:173-174 °C @ Press: 8 Torr
Flash Point:184.6±17.9 °C
Refractive Index:1.540
Water Solubility:Very slightly soluble in water.
Odor:Odorless
Taste:Tasteless
PKA:2.472None
Dissociation Constants:2.472|pKa= 2.47 (conjugate acid)
Collision Cross Section:159.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydrolyzed slowly when boiled with water|ALKALI HYDROXIDES ACCELERATE HYDROLYSIS
Air and Water Reactions:May be sensitive to light and air. Insoluble in water. Slowly hydrolyzed when boiled in water. Also will hydrolyze under high and low pH conditions (NTP, 1992).
Reactive Group:Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
Reactivity Profile:N-BUTYL-P-AMINOBENZOATE is an aminophenyl ester derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Skin sensitization, Category 1
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P333+P317 If skin irritation or rash occurs: Get medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
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