Erlotinib Hydrochloride (Tarceva) 99% white powder GB0255 Greenbo
2 Inquiries
183319-69-9
Pharmaceutical Grade
99%
Shanghai
Greenbo
25kg Drum
2022-07-31
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceErlotinib hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM.
Erlotinib Hydrochloride is the hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation.|A quinazoline derivative and ANTINEOPLASTIC AGENT that functions as a PROTEIN KINASE INHIBITOR for EGFR associated tyrosine kinase. It is used in the treatment of NON-SMALL CELL LUNG CANCER.Basic Info-
Product Name:
Erlotinib hydrochloride
Other Name:4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,hydrochloride (1:1);4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,monohydrochloride;CP 358774;OSI 774;Tarceva;6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride;[6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride;Erlotinib hydrochloride
CAS No.:183319-69-9
Molecular Formula:C22H23N3O4.ClH
InChIKeys:InChIKey=GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Molecular Weight:429.89700
Exact Mass:429.14600
UNII:DA87705X9K
NSC Number:718781
DSSTox ID:DTXSID10171412
NCI Thesaurus Code:C2693
ATC Code:L01EB02
HScode:2933990090
Categories:
Characteristics-
PSA:
74.73000
XLogP3:4.28010
Appearance:White or off-white powder
Melting Point:219-221 °C @ Solvent: Methanol
Boiling Point:553.6ºC at 760 mmHg
Flash Point:288.6ºC
Vapor Pressure:4.52E-12mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
Company Certificates-
international trade license
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FSSC2000
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Erlotinib Hydrochloride
1 KG Jun 23, 2025
Pakistan
ERLOTINIB HCL
3.00 KG Dec 31, 2024 Post an enquiry for this product
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