Pentoxifylline
GMP HALAL KOSHER ISO FDA 3 Inquiries
6493-05-6
Industrial Grade
99%
Dideu
25kg/Cardboard Drum
Yes
2031-12-31
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferencePentoxifylline is a competitive nonselective phosphodiesterase inhibitor.Target: PDEPentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. In addition, pentoxifylline improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Pentoxifylline is also an antagon
Solid
Pentoxifylline is an oxopurine.|Pentoxifylline is a Blood Viscosity Reducer. The physiologic effect of pentoxifylline is by means of Hematologic Activity Alteration.|Pentoxifylline is a xanthine derivative that decreases the viscosity of blood and is used to treat symptoms of intermittent claudication due to peripheral vascular disease. Pentoxifylline has not been associated with serum enzyme elevations during therapy, but in several isolated case reports has been linked to clinically apparent liver injury.|Pentoxifylline is a methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility, and enhances blood flow. In addition, the increased level of cAMP in platelets inhibits platelet aggregation, which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha and interferon-gamma, while it induces Th2-like (T-helper 2) cytokine production, thereby inhibiting Th1-mediated (T-helper 1) inflammatory and autoimmune responses.|A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.CertificatesBasic Info-
Product Name:
Pentoxifylline
Other Name:1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-;Theobromine,1-(5-oxohexyl)-;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;1-(5-Oxohexyl)-3,7-dimethylxanthine;3,7-Dimethyl-1-(5-oxohexyl)xanthine;BL 191;Trental;Pentoxifylline;Dimethyloxohexylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;Pentoxifyllin;Oxpentifylline;Torental;Agapurin Retard;Pentoxiphylline;PTX;Vazofirin;Azupentat;Rentylin;Durapental;NSC 637086;Agapurin;Vasotal;Pexal;EHT 0202;Polfilin;Pentoxyfarm;Pentoxifilline;3,7-Dimethyl-1-(5-oxohexyl)-1H-purine-2,6(3H,7H)-dione;3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)purine-2,6-dione;495419-61-9
CAS No.:6493-05-6
Molecular Formula:C13H18N4O3
InChIKeys:InChIKey=BYPFEZZEUUWMEJ-UHFFFAOYSA-N
Molecular Weight:278.31
Exact Mass:278.31
EC Number:229-374-5
UNII:SD6QCT3TSU
NSC Number:758481|637086
DSSTox ID:DTXSID7023437
NCI Thesaurus Code:C733
ATC Code:C04AD03|C - Cardiovascular system
HScode:2933990090
Categories:
Characteristics-
PSA:
75.5
XLogP3:0.3
Appearance:white solid
Density:1.3 g/cm3
Melting Point:105 °C
Boiling Point:531.3±56.0 °C at 760 mmHg
Flash Point:275.1±31.8 °C
Refractive Index:1.621
Water Solubility:5.17e+00 g/L
Storage Conditions:Store at RT
Toxicity:LD50 orally in mice: 1385 mg/kg (Popendiker)
Collision Cross Section:158.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted
Italy
Pentoxifylline
2 KG Jan 23, 2026
United Kingdom
Pentoxifylline
75 G May 8, 2026
Nigeria
pentoxifylline
1 KG May 4, 2025 Post an enquiry for this product
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