Argatroban 99% white powder GB0292 Greenbo
141396-28-3
Pharmaceutical Grade
99%
Shanghai
Greenbo
25kg Drum
2022-07-31
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceArgatroban monohydrate is a direct, selective thrombin inhibitor.Target: ThrombinArgatroban may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of argatroban is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries [1]. Argatroban, as compared with heparin, appears to enhance
Argatroban anticoagulant is synthesized from L-arginine and photodegrades under light exposure.Basic Info-
Product Name:
Argatroban monohydrate
Other Name:Argatroban (hydrate);Argatroban (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid;Argatroban (350 mg);(2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid hydrate;Argatroban 1-hydrate;AG, SAJ;Agatroban monohydrate;CS-1966
CAS No.:141396-28-3
Molecular Formula:C23H36N6O5S.H2O
InChIKeys:AIEZTKLTLCMZIA-WOXJCXRUNA-N
Molecular Weight:526.65
Exact Mass:526.257
EC Number:2017-001-1
DSSTox ID:DTXSID5057888
Color/Form:white to off-white
HScode:29350090
Categories:
Characteristics-
PSA:
190
XLogP3:log Kow = 1.28 (est)
Appearance:white to off-white
Density:1.5±0.1 g/cm3
Melting Point:176-180°
Flash Point:438.4±37.1 °C
Refractive Index:1.674
Water Solubility:DMSO: ≥20mg/mL
Storage Conditions:2-8°C
Vapor Pressure:1.37X10-17 mm Hg at 25 °C (est)
Toxicity:mouse,LD50,intraperitoneal,475mg/kg (475mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABLOOD: NORMOCYTIC ANEMIABEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 14(Suppl,
Specific rotation:D27 +76.1° (c = 1 in 0.2N HCl)
PH:pH 8.8 (Argatroban solution)
Critical Temperature & Pressure:2-8°C
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Certifications:
international trade license,FSSC2000
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