rotundine
483-14-7
Industrial Grade
99%
25kg/Cardboard Drum
Yes
2022-07-27
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceRotundine is an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 μM and 3.3 μM, respectively. Rotundine is also an antagonist of 5-HT1A with an IC50 of 370 nM.
Tetrahydropalmatine is a berberine alkaloid obtained by formal addition of two molecules of hydrogen to the pyridine ring of palmatine. It has a role as an adrenergic agent, a non-narcotic analgesic and a dopaminergic antagonist. It is a berberine alkaloid and an organic heterotetracyclic compound. It derives from a palmatine.|Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).Basic Info-
Product Name:
(-)-Tetrahydropalmatine
Other Name:6H-Dibenzo[a,g]quinolizine,5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-,(13aS)-;13aα-Berbine,2,3,9,10-tetramethoxy-;Gindarine;6H-Dibenzo[a,g]quinolizine,5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-,(S)-;Cyclanoline,O,O-dimethyl-N-demethyl-;(13aS)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine;Caseanine;(-)-Tetrahydropalmatine;Hyndarine;Palmatine,tetrahydro-,(-)-;Rotundine;(-)-S-Tetrahydropalmatine;Rotundine (Stephania),(-)-;(-)-2,3,9,10-Tetramethoxyberbine;(-)-Rotundine;(S)-Tetrahydropalmatine;l-Tetrahydropalmatine;(-)-Corydalis B;N-Demethyl-O,O′-dimethylcyclanoline;N-Demethyl-O,O′-dimethylsteponine;(13AS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline;605-20-9;11075-91-5;34017-31-7;906324-96-7
CAS No.:483-14-7
Molecular Formula:C21H25NO4
InChIKeys:InChIKey=AEQDJSLRWYMAQI-KRWDZBQOSA-N
Molecular Weight:355.434
Exact Mass:355.43
UNII:3X69CO5I79
Categories:
Characteristics-
PSA:
40.2
XLogP3:3.2
Appearance:Off-white solid
Density:1.2±0.1 g/cm3
Melting Point:142 °C
Boiling Point:482.9°C at 760 mmHg
Flash Point:138.7±25.9 °C
Refractive Index:1.609
Storage Conditions:Refrigerator
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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