 Home > Specialty Chemicals > (2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7h-pyrrolo[2,3-d]pyrimidin-5-yl)methanone for Sale > ARQ-531

ARQ-531

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CAS No.:

2095393-15-8

Content:

99%

Packaging:

Bottle,barrel,cargo,container,etc.

Sample Available:

Yes

Price valid (until):

2026-11-22

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HANGZHOU LEAP CHEM CO., LTD.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C

Average Lead Time:

5 days

Qualification:

Main Products:

Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

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Description

Keywords

2095393-15-8

ARQ-531

Quick Details

ProName:
ARQ-531

CasNo:
2095393-15-8

Appearance:
powder, or liquid

Application:
Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals

DeliveryTime:
5-7 Days

PackAge:
Bottle, barrel, cargo, container, etc.

Port:
Shanghai

Purity:
99

Storage:
Stored in room temperature, ventilated place

Transportation:
By air, ship, express, etc.

LimitNum:
0

Grade:
Industrial Grade

Superiority

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick Response

Details

LEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicals

ECHEMI Editorial Reference

Nemtabrutinib is an orally available reversible inhibitor of Bruton's tyrosine kinase (BTK; Bruton agammaglobulinemia tyrosine kinase), with potential antineoplastic activity. Upon administration, nemtabrutinib non-covalently binds to and inhibits the activity of both the wild-type and the C481S mutated form of BTK, a resistance mutation in the BTK active site in which cysteine is substituted for serine at residue 481. This prevents the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways. This leads to an inhibition of the growth of malignant B-cells that overexpress BTK. Compared to other BTK inhibitors, nemtabrutinib does not require interaction with the BTK C481 site and inhibits the proliferation of cells harboring the BTK C481S mutation. BTK, a member of the Src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed or mutated in B-cell malignancies; it plays an important role in the development, activation, signaling, proliferation and survival of B-lymphocytes.

Basic Info

Product Name:
(2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7h-pyrrolo[2,3-d]pyrimidin-5-yl)methanone

Other Name:
ARQ 531;2095393-15-8;ARQ-531;UNII-JTZ51LIXN4;JTZ51LIXN4;ARQ531;MK1026;(2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7h-pyrrolo[2,3-d]pyrimidin-5-yl)methanone;MK-1026;(2-chloro-4-phenoxyphenyl)-[4-[[(3R,6S)-6-(hydroxymethyl)oxan-3-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone

CAS No.:
2095393-15-8

Molecular Formula:
C25H23ClN4O4

InChIKeys:
JSFCZQSJQXFJDS-QAPCUYQASA-N

Molecular Weight:
478.9

Exact Mass:
478.1407829

UNII:
JTZ51LIXN4

NCI Thesaurus Code:
C138066

Categories:
Seller Information

Business Type:
Trader

Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
5 days

Total Annual Revenue:
Above $100 million

Year of Establishment:
2020

Company Certificates
- ISO
Company Profile
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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ARQ-531

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