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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Umeclidinium bromide for Sale > 1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylMethyl)-1-[2-(phenylMethoxy)ethyl]-, broMide (1:1)
1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylMethyl)-1-[2-(phenylMethoxy)ethyl]-, broMide (1:1) buy - large image1
1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylMethyl)-1-[2-(phenylMethoxy)ethyl]-, broMide (1:1) buy - image1

1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylMethyl)-1-[2-(phenylMethoxy)ethyl]-, broMide (1:1)

Unit Price: Get Latest Price
CAS No.:

869113-09-7

Content:

99%

Packaging:

Bottle,barrel,cargo,container,etc.

Price valid (until):

2026-09-30

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

  • Product Description

  • Seller Information

  • Description
    HANGZHOU LEAP CHEM CO., LTD., with approximately 1814893 visits to its shop, is a reputable Trader that has been providing 1-Azoniabicyclo[2.2.2]octane, 4-(hydroxydiphenylMethyl)-1-[2-(phenylMethoxy)ethyl]-, broMide (1:1) products for 5 years on ECHEMI.
    ECHEMI Editorial Reference
    Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.
    Umeclidinium bromide is a quaternary ammonium salt that is the bromide salt of umeclidinium. Used in combination with vilanterol for long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist. It is a quaternary ammonium salt and an organic bromide salt. It contains an umeclidinium.|Umeclidinium Bromide is the bromide salt form of umeclidinium, a muscarinic receptor antagonist, with bronchodilator activity. Although it does not display selectivity for specific muscarinic receptors, on topical application, umeclidinium acts mainly on M3 muscarinic receptors located on smooth muscle cells, thereby preventing smooth muscle contraction and resulting in bronchodilatory effect.

    Basic Info
    Product Name:

    Umeclidinium bromide

    Other Name:

    1-Azoniabicyclo[2.2.2]octane,4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-,bromide (1:1);1-Azoniabicyclo[2.2.2]octane,4-(hydroxydiphenylmethyl)-1-[2-(phenylmethoxy)ethyl]-,bromide;4-(Hydroxydiphenylmethyl)-1-[2-[(phenylmethyl)oxy]ethyl]-1-azabicyclo[2.2.2]octanium bromide;4-[Hydroxy(diphenyl)methyl]-1-[2-[(phenylmethyl)oxy]ethyl]-1-azoniabicyclo[2.2.2]octane bromide;Umeclidinium bromide;Ellipta;Rolufta Ellipta;Incruse Ellipta

    CAS No.:

    869113-09-7

    Molecular Formula:

    C29H34NO2.Br

    InChIKeys:

    InChIKey=PEJHHXHHNGORMP-UHFFFAOYSA-M

    Molecular Weight:

    508.48976

    Exact Mass:

    507.177277

    EC Number:

    1592732-453-0

    UNII:

    7AN603V4JV

    DSSTox ID:

    DTXSID50235966

    NCI Thesaurus Code:

    C152797

    ATC Code:

    R03AL08|R03BB07|R03AL03|R - Respiratory system

    Characteristics
    PSA:

    29.5

    XLogP3:

    2.10280

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Acute toxicity - Category 4, Inhalation

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H332 Harmful if inhaled

    H400 Very toxic to aquatic life

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P317 Get medical help.

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

    Location:

    Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang

    Payment Terms:

    TT against copy of documents,D/P,L/C

    Average lead Time:

    5

    Total Annual Revenue:

    Above $100 million

    Year of Establishment:

    2020

    Certifications:

    ISO

    Company Profile

    LEAPChem is a specialized fine chemical supplier for research, development and production.

    LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.

    As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.

    Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.


    Methodology: Sound & Stable; Active & Innovative.

    Attitude: Conscientious; Ingenious.

    Goals: Customer's Satisfaction


    We regard client's success as our success.

    At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.

    To achieve this strategic vision, we always push ourselves to exceed our customer's requirement.  By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.

    Welcome to contact us and we look forward to becoming your reliable and preferred partner.

    LEAPChem is a specialized fine chemical supplier for research, development and production.

    LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.

    As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.

    Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.


    Methodology: Sound & Stable; Active & Innovative.

    Attitude: Conscientious; Ingenious.

    Goals: Customer's Satisfaction


    We regard client's success as our success.

    At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.

    To achieve this strategic vision, we always push ourselves to exceed our customer's requirement.  By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.

    Welcome to contact us and we look forward to becoming your reliable and preferred partner.

    ">Company Profile
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