Bis(pinacolato)diboron
2 Inquiries
73183-34-3
99%
Bottle,barrel,cargo,container,etc.
2026-07-09
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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Inquiry History
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DescriptionKeywords
Bis(pinacolato)diboron
73183-34-3
C12H24B2O4
Quick DetailsProName:Bis(pinacolato)diboron
CasNo:73183-34-3
Molecular Formula:C12H24B2O4
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
ProductionCapacity:Metric Ton/Day
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:1 Gram
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
Used Chemicals
- 3-Iodobenzalehyde [I0611]
- Bis(pinacolato)diborane [B1964]
- Palladium(II) Acetate (Purified) [P2161]
- Potassium Acetate [P2786]
- DMF
Procedure
To the solution of 3-iodobenzalehyde (1.16 g, 5.00 mmol) in dry DMF (15.0 mL) were added potassium acetate (981 mg, 10.0 mmol), palladium(II) acetate (112 mg, 0.500 mmol, 10 mol%) and bis(pinacolato)diborane (1.27 g, 5.00 mmol). The reaction mixture was stirred at 80 ºC for 7 h. The reaction mixture was cooled to room temperature and quenched with H2O (15 mL) and saturated NH4Cl aq. (10 mL), then the mixture was extracted twice with hexane : EtOAc = 4 : 1. The combined organic layer was washed with H2O (50 mL) and brine (50 mL), dried over Na2SO4, and concentrated under reduced pressure to afford the crude product as a yellow oil. The crude product was purified by column chromatography on silica-gel (hexane → hexane : EtOAc = 1:1) to afford 3-formylphenylboronic acid pinacol ester as a yellow oil (500 mg, 2.15 mmol, 43%).
Experimenter's Comments
(1) DMF was dried over molecular sieves.
(2) Completion of the reaction was confirmed by TLC (hexane : EtOAc = 1 : 1, Rf = 0.30) and GC.
Analytical Data（3-Formylphenylboronic Acid Pinacol Ester）
1H NMR (400 MHz, CDCl3); δ 10.1 (s, 1H), 8.30 (s, 1H), 8.06 (d, J = 4.0 Hz, 1H), 7.99 (ddd, J = 1.6, 1.8, 7.8 Hz, 1H), 7.53 (t, J = 8.0 Hz, 1H), 1.37 (s, 12H).
Lead Reference
- The bulky side chain of antillatoxin is important for potent toxicity: rational design of photoresponsive cytotoxins based on SAR studies
- K. Okura, S. Matsuoka, M. Inoue, Chem. Commun. 2013, 49, 8024.
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicals
Used Chemicals
- 3-Iodobenzalehyde [I0611]
- Bis(pinacolato)diborane [B1964]
- Palladium(II) Acetate (Purified) [P2161]
- Potassium Acetate [P2786]
- DMF
Procedure
To the solution of 3-iodobenzalehyde (1.16 g, 5.00 mmol) in dry DMF (15.0 mL) were added potassium acetate (981 mg, 10.0 mmol), palladium(II) acetate (112 mg, 0.500 mmol, 10 mol%) and bis(pinacolato)diborane (1.27 g, 5.00 mmol). The reaction mixture was stirred at 80 ºC for 7 h. The reaction mixture was cooled to room temperature and quenched with H2O (15 mL) and saturated NH4Cl aq. (10 mL), then the mixture was extracted twice with hexane : EtOAc = 4 : 1. The combined organic layer was washed with H2O (50 mL) and brine (50 mL), dried over Na2SO4, and concentrated under reduced pressure to afford the crude product as a yellow oil. The crude product was purified by column chromatography on silica-gel (hexane → hexane : EtOAc = 1:1) to afford 3-formylphenylboronic acid pinacol ester as a yellow oil (500 mg, 2.15 mmol, 43%).
Experimenter's Comments
(1) DMF was dried over molecular sieves.
(2) Completion of the reaction was confirmed by TLC (hexane : EtOAc = 1 : 1, Rf = 0.30) and GC.
Analytical Data（3-Formylphenylboronic Acid Pinacol Ester）
1H NMR (400 MHz, CDCl3); δ 10.1 (s, 1H), 8.30 (s, 1H), 8.06 (d, J = 4.0 Hz, 1H), 7.99 (ddd, J = 1.6, 1.8, 7.8 Hz, 1H), 7.53 (t, J = 8.0 Hz, 1H), 1.37 (s, 12H).
Lead Reference
- The bulky side chain of antillatoxin is important for potent toxicity: rational design of photoresponsive cytotoxins based on SAR studies
- K. Okura, S. Matsuoka, M. Inoue, Chem. Commun. 2013, 49, 8024.
Basic Info-
Product Name:
Bis(pinacolato)diborane
Other Name:2,2′-Bi-1,3,2-dioxaborolane,4,4,4′,4′,5,5,5′,5′-octamethyl-;1,3,2-Dioxaborolane,bimol. deriv.;4,4,4′,4′,5,5,5′,5′-Octamethyl-2,2′-bi-1,3,2-dioxaborolane;Bis(pinacolato)diborane;B2Pin2;Bis(pinacolato)diborane(4);4,4,5,5,4′,4′,5′,5′-Octamethyl-[2,2′]bi[[1,3,2]dioxaborolanyl];Diboron pinacol ester;Pinacol diborane;4,4,5,5-Tetramethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane;2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4,4,4′,4′,5,5,5′,5′-Octamethyl-2,2′-bi-1,3,2-dioxaborolan;Bis(pinacolate)diboron;Bis(pinacolato) diborate;4,4′,5,5′-Octamethyl-2,2′-bi-1,3,2-dioxaborolane;Dipinacoldiboron;4,4,4′,4′,5,5,5′,5′-Octamethyl-2,2′-bis(1,3,2-dioxaborolane);4,4,5,5,4′,4′,5′,5′-Octamethyl-2,2′-bis(1,3,2-dioxaborolane);Bis-pinacoldiboron;4,4,5,5-Tetramethyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane;Bis(4,4,5,5-tetramethyl-[1,3]dioxolan-2-yl)borane;4,4,4′,4′,5,5,5′,5′-Octamethyl-2,2′-bi-1,3,2-dioxaborolane [B2(pin)2];4,4,5,5-Tetramethyl-1,3,2-dioxaborane;4,4,5,5,4′,4′,5′,5′-octamethyl-2,2′-bi(1,3,2-dioxaborolane);Bis(pinanolato)diboron;4,4,5,5-Tetramethyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolan;Octamethyl-2,2′-bi(1,3,2-dioxaborolane);4,4,4′,4′,5,5,5′,5′-Octamethyl-2,2′-bi(1,3,2-dioxaborolane);1106313-74-9
CAS No.:73183-34-3
Molecular Formula:C12H24B2O4
InChIKeys:InChIKey=IPWKHHSGDUIRAH-UHFFFAOYSA-N
Molecular Weight:253.94
Exact Mass:253.94
BRN:7703552
EC Number:-0
UNII:I906W26P4U
DSSTox ID:DTXSID30369935
HScode:2934999090
Categories:
Characteristics-
PSA:
36.9
XLogP3:2.24920
Appearance:White Powder or Platelets
Density:1.0±0.1 g/cm3
Melting Point:115-117 °C @ Solvent: Hexane
Boiling Point:222.6°C at 760 mmHg
Flash Point:88.4±18.2 °C
Refractive Index:1.432
Water Solubility:soluble in tetrahydrofuran, dichloromethane, toluene, hexane and heptane. Insoluble in water.
Storage Conditions:0-6°C
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction
We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
India
Bis pinacolato diboron
1 MT Nov 22, 2025 
Netherlands
BIS(PINACOLATO)DIBORON
1 MT Apr 26, 2024 Post an enquiry for this product
